Protective effects of bifidobacteria against enteropathogens
Summary Recent major advances in metagenomics and metabolomics technologies have enabled us to collect more data on the gut microbiome and metabolome to evaluate its influence on host health. In this short opinion article, we have chosen to focus on summarizing the protective mechanisms of bifidobac...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-11-01
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| Series: | Microbial Biotechnology |
| Online Access: | https://doi.org/10.1111/1751-7915.13460 |
| _version_ | 1818494405661687808 |
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| author | Wanping Aw Shinji Fukuda |
| author_facet | Wanping Aw Shinji Fukuda |
| author_sort | Wanping Aw |
| collection | DOAJ |
| description | Summary Recent major advances in metagenomics and metabolomics technologies have enabled us to collect more data on the gut microbiome and metabolome to evaluate its influence on host health. In this short opinion article, we have chosen to focus on summarizing the protective mechanisms of bifidobacteria, a highly regarded probiotic, and it's metabolite: acetate; against enteropathogens, specifically in the E. coli O157:H7 mice model. We advocate for using a novel approach metabologenomics, which is an integration of metagenomic and metabolomic information on a systems biology‐wide approach to better understand this interplay between gut microbiome and host metabolism. |
| first_indexed | 2024-12-10T18:05:43Z |
| format | Article |
| id | doaj.art-41ce8bdfa3554a87b2e488f4a63cc814 |
| institution | Directory Open Access Journal |
| issn | 1751-7915 |
| language | English |
| last_indexed | 2024-12-10T18:05:43Z |
| publishDate | 2019-11-01 |
| publisher | Wiley |
| record_format | Article |
| series | Microbial Biotechnology |
| spelling | doaj.art-41ce8bdfa3554a87b2e488f4a63cc8142022-12-22T01:38:36ZengWileyMicrobial Biotechnology1751-79152019-11-011261097110010.1111/1751-7915.13460Protective effects of bifidobacteria against enteropathogensWanping Aw0Shinji Fukuda1Institute for Advanced Biosciences Keio University 246‐2 Mizukami, Kakuganji Tsuruoka Yamagata 997‐0052 JapanInstitute for Advanced Biosciences Keio University 246‐2 Mizukami, Kakuganji Tsuruoka Yamagata 997‐0052 JapanSummary Recent major advances in metagenomics and metabolomics technologies have enabled us to collect more data on the gut microbiome and metabolome to evaluate its influence on host health. In this short opinion article, we have chosen to focus on summarizing the protective mechanisms of bifidobacteria, a highly regarded probiotic, and it's metabolite: acetate; against enteropathogens, specifically in the E. coli O157:H7 mice model. We advocate for using a novel approach metabologenomics, which is an integration of metagenomic and metabolomic information on a systems biology‐wide approach to better understand this interplay between gut microbiome and host metabolism.https://doi.org/10.1111/1751-7915.13460 |
| spellingShingle | Wanping Aw Shinji Fukuda Protective effects of bifidobacteria against enteropathogens Microbial Biotechnology |
| title | Protective effects of bifidobacteria against enteropathogens |
| title_full | Protective effects of bifidobacteria against enteropathogens |
| title_fullStr | Protective effects of bifidobacteria against enteropathogens |
| title_full_unstemmed | Protective effects of bifidobacteria against enteropathogens |
| title_short | Protective effects of bifidobacteria against enteropathogens |
| title_sort | protective effects of bifidobacteria against enteropathogens |
| url | https://doi.org/10.1111/1751-7915.13460 |
| work_keys_str_mv | AT wanpingaw protectiveeffectsofbifidobacteriaagainstenteropathogens AT shinjifukuda protectiveeffectsofbifidobacteriaagainstenteropathogens |