Generation and Functional Characterization of PLAP CAR-T Cells against Cervical Cancer Cells

Generation and Functional Characterization of PLAP CAR-T Cells against Cervical Cancer Cells

Chimeric antigen receptor (CAR) T-cell therapy is one of the cancer treatment modalities that has recently shown promising results in treating hematopoietic malignancies. However, one of the obstacles that need to be addressed in solid tumors is the on-target and off-tumor cytotoxicity due to the la...

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Bibliographic Details
Main Authors: Vahid Yekehfallah, Saghar Pahlavanneshan, Ali Sayadmanesh, Zahra Momtahan, Bin Ma, Mohsen Basiri
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomolecules
Subjects:
cervical cancer
chimeric antigen receptor
genetic engineering
T-cell therapy
Online Access:https://www.mdpi.com/2218-273X/12/9/1296

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