Birth outcomes and early growth patterns associated with age at adiposity rebound: the Ma’anshan birth cohort (MABC) study
Abstract Objective Early onset of adiposity rebound (AR) is considered an early indicator of obesity risk. Our objective was to investigate the association of birth outcomes and early physical growth patterns with early AR in children. Methods Study subjects (n = 2705) were enrolled from the Ma’ansh...
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| Format: | Article |
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BMC
2023-12-01
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| Series: | BMC Public Health |
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| Online Access: | https://doi.org/10.1186/s12889-023-17236-9 |
| _version_ | 1797397668672045056 |
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| author | Jixing Zhou Yuzhu Teng Shanshan Zhang Mengting Yang Shuangqin Yan Fangbiao Tao Kun Huang |
| author_facet | Jixing Zhou Yuzhu Teng Shanshan Zhang Mengting Yang Shuangqin Yan Fangbiao Tao Kun Huang |
| author_sort | Jixing Zhou |
| collection | DOAJ |
| description | Abstract Objective Early onset of adiposity rebound (AR) is considered an early indicator of obesity risk. Our objective was to investigate the association of birth outcomes and early physical growth patterns with early AR in children. Methods Study subjects (n = 2705) were enrolled from the Ma’anshan birth cohort (MABC). The body mass index (BMI), head circumference, waist circumference, and body fat were collected. Rapid weight gain (RWG) was defined by the change in weight standard-deviation score in the first two years of life. Group-based trajectory modeling (GBTM) was used to determine children’s physical growth trajectories. The age of AR was fitted using fractional polynomial function models. Results Children with very high BMI trajectories (RR = 2.83; 95% CI 2.33 to 1.40), rising BMI trajectories (RR = 3.15; 95% CI 2.66 to 3.72), high waist circumference trajectories (RR = 4.17; 95% CI 3.43 to 5.06), and high body fat trajectories (RR = 3.01; 95% CI 2.62 to 3.46) before 72 months of age were at a greater risk of experiencing early AR. Low birth weight (LBW) (RR = 1.86; 95% CI 1.28 to 2.51), preterm birth (PTB) (RR = 1.50; 95% CI 1.17 to 1.93), and small for gestational age (SGA) (RR = 1.37; 95% CI 1.14 to 1.64) associated with increased risk of early AR. Moreover, infants experiencing RWG (RR = 1.59; 95% CI 1.40 to 1.83), low BMI trajectories (RR = 1.27; 95% CI 1.06 to 1.53) and rising BMI trajectories (RR = 1.50; 95% CI 1.22 to 1.84) in the first two years were at higher risk of developing early AR subsequently. Compared to the group with non-early AR, the BMI of children with early AR tended to be lower first (from birth to 6 months of age) and then higher (from 18 to 72 months of age). Conclusions Children with overall high BMI, high waist circumference, and high body fat before 72 months of age are more likely to experience early AR, but infants with low BMI trajectories, rising BMI trajectories and infants experiencing RWG in the first two years of life similarly increase the risk of early AR. These results can help to understand the early factors and processes that lead to metabolic risks. |
| first_indexed | 2024-03-09T01:14:29Z |
| format | Article |
| id | doaj.art-41d458c0f37e442ca95d025b8199ec08 |
| institution | Directory Open Access Journal |
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| language | English |
| last_indexed | 2024-03-09T01:14:29Z |
| publishDate | 2023-12-01 |
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| spelling | doaj.art-41d458c0f37e442ca95d025b8199ec082023-12-10T12:34:24ZengBMCBMC Public Health1471-24582023-12-0123111410.1186/s12889-023-17236-9Birth outcomes and early growth patterns associated with age at adiposity rebound: the Ma’anshan birth cohort (MABC) studyJixing Zhou0Yuzhu Teng1Shanshan Zhang2Mengting Yang3Shuangqin Yan4Fangbiao Tao5Kun Huang6Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical UniversityDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical UniversityDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical UniversityDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical UniversityDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical UniversityDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical UniversityDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical UniversityAbstract Objective Early onset of adiposity rebound (AR) is considered an early indicator of obesity risk. Our objective was to investigate the association of birth outcomes and early physical growth patterns with early AR in children. Methods Study subjects (n = 2705) were enrolled from the Ma’anshan birth cohort (MABC). The body mass index (BMI), head circumference, waist circumference, and body fat were collected. Rapid weight gain (RWG) was defined by the change in weight standard-deviation score in the first two years of life. Group-based trajectory modeling (GBTM) was used to determine children’s physical growth trajectories. The age of AR was fitted using fractional polynomial function models. Results Children with very high BMI trajectories (RR = 2.83; 95% CI 2.33 to 1.40), rising BMI trajectories (RR = 3.15; 95% CI 2.66 to 3.72), high waist circumference trajectories (RR = 4.17; 95% CI 3.43 to 5.06), and high body fat trajectories (RR = 3.01; 95% CI 2.62 to 3.46) before 72 months of age were at a greater risk of experiencing early AR. Low birth weight (LBW) (RR = 1.86; 95% CI 1.28 to 2.51), preterm birth (PTB) (RR = 1.50; 95% CI 1.17 to 1.93), and small for gestational age (SGA) (RR = 1.37; 95% CI 1.14 to 1.64) associated with increased risk of early AR. Moreover, infants experiencing RWG (RR = 1.59; 95% CI 1.40 to 1.83), low BMI trajectories (RR = 1.27; 95% CI 1.06 to 1.53) and rising BMI trajectories (RR = 1.50; 95% CI 1.22 to 1.84) in the first two years were at higher risk of developing early AR subsequently. Compared to the group with non-early AR, the BMI of children with early AR tended to be lower first (from birth to 6 months of age) and then higher (from 18 to 72 months of age). Conclusions Children with overall high BMI, high waist circumference, and high body fat before 72 months of age are more likely to experience early AR, but infants with low BMI trajectories, rising BMI trajectories and infants experiencing RWG in the first two years of life similarly increase the risk of early AR. These results can help to understand the early factors and processes that lead to metabolic risks.https://doi.org/10.1186/s12889-023-17236-9Adiposity reboundBirth outcomeRapid weight gainBMI trajectoryChildren |
| spellingShingle | Jixing Zhou Yuzhu Teng Shanshan Zhang Mengting Yang Shuangqin Yan Fangbiao Tao Kun Huang Birth outcomes and early growth patterns associated with age at adiposity rebound: the Ma’anshan birth cohort (MABC) study BMC Public Health Adiposity rebound Birth outcome Rapid weight gain BMI trajectory Children |
| title | Birth outcomes and early growth patterns associated with age at adiposity rebound: the Ma’anshan birth cohort (MABC) study |
| title_full | Birth outcomes and early growth patterns associated with age at adiposity rebound: the Ma’anshan birth cohort (MABC) study |
| title_fullStr | Birth outcomes and early growth patterns associated with age at adiposity rebound: the Ma’anshan birth cohort (MABC) study |
| title_full_unstemmed | Birth outcomes and early growth patterns associated with age at adiposity rebound: the Ma’anshan birth cohort (MABC) study |
| title_short | Birth outcomes and early growth patterns associated with age at adiposity rebound: the Ma’anshan birth cohort (MABC) study |
| title_sort | birth outcomes and early growth patterns associated with age at adiposity rebound the ma anshan birth cohort mabc study |
| topic | Adiposity rebound Birth outcome Rapid weight gain BMI trajectory Children |
| url | https://doi.org/10.1186/s12889-023-17236-9 |
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