Comparison of human B cell activation by TLR7 and TLR9 agonists

<p>Abstract</p> <p>Background</p> <p>Human B cells and plasmacytoid dendritic cells (pDC) are the only cells known to express both TLR7 and TLR9. Plasmacytoid dendritic cells are the primary IFN-α producing cells in response to TLR7 and TLR9 agonists. The direct effects...

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Bibliographic Details
Main Authors: Neys Lori, Riter Christie L, Vasilakos John P, Hanten John A, Lipson Kenneth E, Alkan Sefik S, Birmachu Woubalem
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/9/39