Visual barcodes for clonal-multiplexing of live microscopy-based assays
Multiplex analyses of samples allow understanding complex processes in cancer initiation, progression and therapy response. Here, the authors present a fluorescence imaging-based visual barcode for livecell clonal-multiplexing which allows identifying signalling pathways clusters in response to diff...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-30008-0 |
| _version_ | 1811341231646572544 |
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| author | Tom Kaufman Erez Nitzan Nir Firestein Miriam Bracha Ginzberg Seshu Iyengar Nish Patel Rotem Ben-Hamo Ziv Porat Jaryd Hunter Andreas Hilfinger Varda Rotter Ran Kafri Ravid Straussman |
| author_facet | Tom Kaufman Erez Nitzan Nir Firestein Miriam Bracha Ginzberg Seshu Iyengar Nish Patel Rotem Ben-Hamo Ziv Porat Jaryd Hunter Andreas Hilfinger Varda Rotter Ran Kafri Ravid Straussman |
| author_sort | Tom Kaufman |
| collection | DOAJ |
| description | Multiplex analyses of samples allow understanding complex processes in cancer initiation, progression and therapy response. Here, the authors present a fluorescence imaging-based visual barcode for livecell clonal-multiplexing which allows identifying signalling pathways clusters in response to different chemotherapy compounds. |
| first_indexed | 2024-04-13T18:53:29Z |
| format | Article |
| id | doaj.art-41dba124b5ec489ea70767c6b7eafc68 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-13T18:53:29Z |
| publishDate | 2022-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-41dba124b5ec489ea70767c6b7eafc682022-12-22T02:34:20ZengNature PortfolioNature Communications2041-17232022-05-0113111710.1038/s41467-022-30008-0Visual barcodes for clonal-multiplexing of live microscopy-based assaysTom Kaufman0Erez Nitzan1Nir Firestein2Miriam Bracha Ginzberg3Seshu Iyengar4Nish Patel5Rotem Ben-Hamo6Ziv Porat7Jaryd Hunter8Andreas Hilfinger9Varda Rotter10Ran Kafri11Ravid Straussman12Department of Molecular Cell Biology, Weizmann Institute of ScienceDepartment of Molecular Cell Biology, Weizmann Institute of ScienceDepartment of Molecular Cell Biology, Weizmann Institute of ScienceProgramme in Cell Biology, The Hospital for Sick ChildrenDepartment of Chemical and Physical Sciences, University of TorontoProgramme in Cell Biology, The Hospital for Sick ChildrenDepartment of Molecular Cell Biology, Weizmann Institute of ScienceFlow Cytometry Unit, Life Sciences Core Facilities, Weizmann Institute of ScienceProgramme in Cell Biology, The Hospital for Sick ChildrenDepartment of Chemical and Physical Sciences, University of TorontoDepartment of Molecular Cell Biology, Weizmann Institute of ScienceProgramme in Cell Biology, The Hospital for Sick ChildrenDepartment of Molecular Cell Biology, Weizmann Institute of ScienceMultiplex analyses of samples allow understanding complex processes in cancer initiation, progression and therapy response. Here, the authors present a fluorescence imaging-based visual barcode for livecell clonal-multiplexing which allows identifying signalling pathways clusters in response to different chemotherapy compounds.https://doi.org/10.1038/s41467-022-30008-0 |
| spellingShingle | Tom Kaufman Erez Nitzan Nir Firestein Miriam Bracha Ginzberg Seshu Iyengar Nish Patel Rotem Ben-Hamo Ziv Porat Jaryd Hunter Andreas Hilfinger Varda Rotter Ran Kafri Ravid Straussman Visual barcodes for clonal-multiplexing of live microscopy-based assays Nature Communications |
| title | Visual barcodes for clonal-multiplexing of live microscopy-based assays |
| title_full | Visual barcodes for clonal-multiplexing of live microscopy-based assays |
| title_fullStr | Visual barcodes for clonal-multiplexing of live microscopy-based assays |
| title_full_unstemmed | Visual barcodes for clonal-multiplexing of live microscopy-based assays |
| title_short | Visual barcodes for clonal-multiplexing of live microscopy-based assays |
| title_sort | visual barcodes for clonal multiplexing of live microscopy based assays |
| url | https://doi.org/10.1038/s41467-022-30008-0 |
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