The Stability of Gene Selection in Microarray Experiments
This paper addresses the issue of the stability of lists of genes identified as differentially expressed in microarray experiments. The similarities be- tween gene rankings yielded by various gene selection methods performed with resampled datasets were assessed. The mean percentage of overlapping g...
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2013-12-01
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| Series: | Studies in Logic, Grammar and Rhetoric |
| Online Access: | https://doi.org/10.2478/slgr-2013-0040 |
| _version_ | 1818605788120219648 |
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| author | Wietlicka-Piszcz Magdalena |
| author_facet | Wietlicka-Piszcz Magdalena |
| author_sort | Wietlicka-Piszcz Magdalena |
| collection | DOAJ |
| description | This paper addresses the issue of the stability of lists of genes identified as differentially expressed in microarray experiments. The similarities be- tween gene rankings yielded by various gene selection methods performed with resampled datasets were assessed. The mean percentage of overlapping genes for two rankings varied from 10 to 90% depending on the applied gene selection method and the size of the list. The assessment of the stability of obtained gene rankings seems to be relevant in the analysis of microarray data. |
| first_indexed | 2024-12-16T14:00:31Z |
| format | Article |
| id | doaj.art-41dcb1bae3da4c1ab2c5ba4aac51e735 |
| institution | Directory Open Access Journal |
| issn | 0860-150X |
| language | English |
| last_indexed | 2024-12-16T14:00:31Z |
| publishDate | 2013-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Studies in Logic, Grammar and Rhetoric |
| spelling | doaj.art-41dcb1bae3da4c1ab2c5ba4aac51e7352022-12-21T22:29:06ZengSciendoStudies in Logic, Grammar and Rhetoric0860-150X2013-12-013518710110.2478/slgr-2013-0040The Stability of Gene Selection in Microarray ExperimentsWietlicka-Piszcz Magdalena0Department of Theoretical Backgrounds of Biomedical Science and Medical Informatics, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University, PolandThis paper addresses the issue of the stability of lists of genes identified as differentially expressed in microarray experiments. The similarities be- tween gene rankings yielded by various gene selection methods performed with resampled datasets were assessed. The mean percentage of overlapping genes for two rankings varied from 10 to 90% depending on the applied gene selection method and the size of the list. The assessment of the stability of obtained gene rankings seems to be relevant in the analysis of microarray data.https://doi.org/10.2478/slgr-2013-0040 |
| spellingShingle | Wietlicka-Piszcz Magdalena The Stability of Gene Selection in Microarray Experiments Studies in Logic, Grammar and Rhetoric |
| title | The Stability of Gene Selection in Microarray Experiments |
| title_full | The Stability of Gene Selection in Microarray Experiments |
| title_fullStr | The Stability of Gene Selection in Microarray Experiments |
| title_full_unstemmed | The Stability of Gene Selection in Microarray Experiments |
| title_short | The Stability of Gene Selection in Microarray Experiments |
| title_sort | stability of gene selection in microarray experiments |
| url | https://doi.org/10.2478/slgr-2013-0040 |
| work_keys_str_mv | AT wietlickapiszczmagdalena thestabilityofgeneselectioninmicroarrayexperiments AT wietlickapiszczmagdalena stabilityofgeneselectioninmicroarrayexperiments |