Retinal cone photoreceptors require phosducin-like protein 1 for G protein complex assembly and signaling.

Retinal cone photoreceptors require phosducin-like protein 1 for G protein complex assembly and signaling.

G protein β subunits (Gβ) play essential roles in phototransduction as part of G protein βγ (Gβγ) and regulator of G protein signaling 9 (RGS9)-Gβ5 heterodimers. Both are obligate dimers that rely on the cytosolic chaperone CCT and its co-chaperone PhLP1 to form complexes from their nascent polypept...

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Bibliographic Details
Main Authors: Christopher M Tracy, Alexander V Kolesnikov, Devon R Blake, Ching-Kang Chen, Wolfgang Baehr, Vladimir J Kefalov, Barry M Willardson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4319785?pdf=render

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