Effects of infection history on dengue virus infection and pathogenicity
Lack of knowledge of individual infection history hinders understanding of immunological interactions among DENV serotypes. Here, the authors introduce a framework to infer the relationship between unobserved infection history and subsequent infection and disease risk, and find complex dependencies.
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-09193-y |
| _version_ | 1818683358246338560 |
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| author | Tim K. Tsang Samson L. Ghebremariam Lionel Gresh Aubree Gordon M. Elizabeth Halloran Leah C. Katzelnick Diana Patricia Rojas Guillermina Kuan Angel Balmaseda Jonathan Sugimoto Eva Harris Ira M. Longini Yang Yang |
| author_facet | Tim K. Tsang Samson L. Ghebremariam Lionel Gresh Aubree Gordon M. Elizabeth Halloran Leah C. Katzelnick Diana Patricia Rojas Guillermina Kuan Angel Balmaseda Jonathan Sugimoto Eva Harris Ira M. Longini Yang Yang |
| author_sort | Tim K. Tsang |
| collection | DOAJ |
| description | Lack of knowledge of individual infection history hinders understanding of immunological interactions among DENV serotypes. Here, the authors introduce a framework to infer the relationship between unobserved infection history and subsequent infection and disease risk, and find complex dependencies. |
| first_indexed | 2024-12-17T10:33:28Z |
| format | Article |
| id | doaj.art-41de2292faac4ea497c6bcb645c19f5d |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-17T10:33:28Z |
| publishDate | 2019-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-41de2292faac4ea497c6bcb645c19f5d2022-12-21T21:52:28ZengNature PortfolioNature Communications2041-17232019-03-011011910.1038/s41467-019-09193-yEffects of infection history on dengue virus infection and pathogenicityTim K. Tsang0Samson L. Ghebremariam1Lionel Gresh2Aubree Gordon3M. Elizabeth Halloran4Leah C. Katzelnick5Diana Patricia Rojas6Guillermina Kuan7Angel Balmaseda8Jonathan Sugimoto9Eva Harris10Ira M. Longini11Yang Yang12Department of Biostatistics, College of Public Health and Health Professions, University of FloridaDepartment of Biostatistics, College of Public Health and Health Professions, University of FloridaSustainable Sciences InstituteDepartment of Epidemiology, School of Public Health, University of MichiganVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research CenterDivision of Infectious Diseases and Vaccinology, School of Public Health, University of CaliforniaDepartment of Biostatistics, College of Public Health and Health Professions, University of FloridaCentro de Salud Sócrates Flores Vivas, Ministry of HealthLaboratorio Nacional de Virología, Centro Nacional de Diagnóstico y Referencia, Ministry of HealthVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research CenterDivision of Infectious Diseases and Vaccinology, School of Public Health, University of CaliforniaDepartment of Biostatistics, College of Public Health and Health Professions, University of FloridaDepartment of Biostatistics, College of Public Health and Health Professions, University of FloridaLack of knowledge of individual infection history hinders understanding of immunological interactions among DENV serotypes. Here, the authors introduce a framework to infer the relationship between unobserved infection history and subsequent infection and disease risk, and find complex dependencies.https://doi.org/10.1038/s41467-019-09193-y |
| spellingShingle | Tim K. Tsang Samson L. Ghebremariam Lionel Gresh Aubree Gordon M. Elizabeth Halloran Leah C. Katzelnick Diana Patricia Rojas Guillermina Kuan Angel Balmaseda Jonathan Sugimoto Eva Harris Ira M. Longini Yang Yang Effects of infection history on dengue virus infection and pathogenicity Nature Communications |
| title | Effects of infection history on dengue virus infection and pathogenicity |
| title_full | Effects of infection history on dengue virus infection and pathogenicity |
| title_fullStr | Effects of infection history on dengue virus infection and pathogenicity |
| title_full_unstemmed | Effects of infection history on dengue virus infection and pathogenicity |
| title_short | Effects of infection history on dengue virus infection and pathogenicity |
| title_sort | effects of infection history on dengue virus infection and pathogenicity |
| url | https://doi.org/10.1038/s41467-019-09193-y |
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