Effects of infection history on dengue virus infection and pathogenicity
Lack of knowledge of individual infection history hinders understanding of immunological interactions among DENV serotypes. Here, the authors introduce a framework to infer the relationship between unobserved infection history and subsequent infection and disease risk, and find complex dependencies.
Main Authors: | Tim K. Tsang, Samson L. Ghebremariam, Lionel Gresh, Aubree Gordon, M. Elizabeth Halloran, Leah C. Katzelnick, Diana Patricia Rojas, Guillermina Kuan, Angel Balmaseda, Jonathan Sugimoto, Eva Harris, Ira M. Longini, Yang Yang |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-09193-y |
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