Bone Mineral Density in Iranian Kidney Graft Recipients and Its Relation to Biochemical and PTH Serum Levels

Little is known about relation of transplantation and bone. We conducted a study to find out the frequency and predictors of osteoporosis in kidney transplanted patients in Iran. DEXA (DPX-MD, GE, Lunar corporation, USA) used for BMD of 61 kidney transplanted patients. Calcium, phosphate, alkaline p...

Full description

Bibliographic Details
Main Authors: M Mahdavi, Z Hamidi, A Soltani, M Sedaghat, M Lessan- Pezeshki, B Larijani
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2004-11-01
Series:Iranian Journal of Public Health
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/2419.pdf&manuscript_id=2419
_version_ 1819142686003691520
author M Mahdavi
Z Hamidi
A Soltani
M Sedaghat
M Lessan- Pezeshki
B Larijani
author_facet M Mahdavi
Z Hamidi
A Soltani
M Sedaghat
M Lessan- Pezeshki
B Larijani
author_sort M Mahdavi
collection DOAJ
description Little is known about relation of transplantation and bone. We conducted a study to find out the frequency and predictors of osteoporosis in kidney transplanted patients in Iran. DEXA (DPX-MD, GE, Lunar corporation, USA) used for BMD of 61 kidney transplanted patients. Calcium, phosphate, alkaline phosphatase, BUN, creatinine and PTH, were also measured. Fourty four percent of patients were men (27). Mean±SD of age of men and women was 44.3±10.44 and 40/7± 13.77, respectively. Mean±SD of transplant duration was 33.9± 33. 2 months Mean±SD of dialysis time was 12±14 months. 29.5% of patients had osteoporosis. Osteoporosis was significantly higher in subjects with BMI less than 19 kg/m2 (P= 0.007). Alkaline phosphatase had a negative relation with osteoporosis in neck (P= 0.001). Other parameters had no significant relationship with osteoporosis. High prevalence of osteoporosis found in Iranian kidney graft recipients. Screening and therapeutic intervention in these patients is urgently needed.
first_indexed 2024-12-22T12:14:17Z
format Article
id doaj.art-41e60d0c0a0445ffb3464c15e5384139
institution Directory Open Access Journal
issn 2251-6085
language English
last_indexed 2024-12-22T12:14:17Z
publishDate 2004-11-01
publisher Tehran University of Medical Sciences
record_format Article
series Iranian Journal of Public Health
spelling doaj.art-41e60d0c0a0445ffb3464c15e53841392022-12-21T18:26:12ZengTehran University of Medical SciencesIranian Journal of Public Health2251-60852004-11-017075Bone Mineral Density in Iranian Kidney Graft Recipients and Its Relation to Biochemical and PTH Serum LevelsM MahdaviZ HamidiA SoltaniM SedaghatM Lessan- PezeshkiB LarijaniLittle is known about relation of transplantation and bone. We conducted a study to find out the frequency and predictors of osteoporosis in kidney transplanted patients in Iran. DEXA (DPX-MD, GE, Lunar corporation, USA) used for BMD of 61 kidney transplanted patients. Calcium, phosphate, alkaline phosphatase, BUN, creatinine and PTH, were also measured. Fourty four percent of patients were men (27). Mean±SD of age of men and women was 44.3±10.44 and 40/7± 13.77, respectively. Mean±SD of transplant duration was 33.9± 33. 2 months Mean±SD of dialysis time was 12±14 months. 29.5% of patients had osteoporosis. Osteoporosis was significantly higher in subjects with BMI less than 19 kg/m2 (P= 0.007). Alkaline phosphatase had a negative relation with osteoporosis in neck (P= 0.001). Other parameters had no significant relationship with osteoporosis. High prevalence of osteoporosis found in Iranian kidney graft recipients. Screening and therapeutic intervention in these patients is urgently needed.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/2419.pdf&manuscript_id=2419
spellingShingle M Mahdavi
Z Hamidi
A Soltani
M Sedaghat
M Lessan- Pezeshki
B Larijani
Bone Mineral Density in Iranian Kidney Graft Recipients and Its Relation to Biochemical and PTH Serum Levels
Iranian Journal of Public Health
title Bone Mineral Density in Iranian Kidney Graft Recipients and Its Relation to Biochemical and PTH Serum Levels
title_full Bone Mineral Density in Iranian Kidney Graft Recipients and Its Relation to Biochemical and PTH Serum Levels
title_fullStr Bone Mineral Density in Iranian Kidney Graft Recipients and Its Relation to Biochemical and PTH Serum Levels
title_full_unstemmed Bone Mineral Density in Iranian Kidney Graft Recipients and Its Relation to Biochemical and PTH Serum Levels
title_short Bone Mineral Density in Iranian Kidney Graft Recipients and Its Relation to Biochemical and PTH Serum Levels
title_sort bone mineral density in iranian kidney graft recipients and its relation to biochemical and pth serum levels
url http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/2419.pdf&manuscript_id=2419
work_keys_str_mv AT mmahdavi bonemineraldensityiniraniankidneygraftrecipientsanditsrelationtobiochemicalandpthserumlevels
AT zhamidi bonemineraldensityiniraniankidneygraftrecipientsanditsrelationtobiochemicalandpthserumlevels
AT asoltani bonemineraldensityiniraniankidneygraftrecipientsanditsrelationtobiochemicalandpthserumlevels
AT msedaghat bonemineraldensityiniraniankidneygraftrecipientsanditsrelationtobiochemicalandpthserumlevels
AT mlessanpezeshki bonemineraldensityiniraniankidneygraftrecipientsanditsrelationtobiochemicalandpthserumlevels
AT blarijani bonemineraldensityiniraniankidneygraftrecipientsanditsrelationtobiochemicalandpthserumlevels