Primary NK/T cell lymphoma nasal type of the colon
Since nasal NK/T-cell lymphoma and NK/T-cell lymphoma nasal type are rare diseases, colonic involvement has seldom been seen. We report a case of a patient with a primary NK/T-cell lymphoma nasal type of the colon. The patient had no history of malignant diseases and was diagnosed after exhaustive s...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2013-02-01
|
| Series: | Rare Tumors |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/rt/article/view/4606 |
| _version_ | 1818838076507553792 |
|---|---|
| author | Ana María Chirife Juan Alberto Cicco Marta Elisa Zerga Claudia Érica Casali Mercedes del Olmo María de los Ángeles Vicente Repáraz Gonzalo Martín Garate Carolina Valeria Mahuad Erica Rojas Bilbao |
| author_facet | Ana María Chirife Juan Alberto Cicco Marta Elisa Zerga Claudia Érica Casali Mercedes del Olmo María de los Ángeles Vicente Repáraz Gonzalo Martín Garate Carolina Valeria Mahuad Erica Rojas Bilbao |
| author_sort | Ana María Chirife |
| collection | DOAJ |
| description | Since nasal NK/T-cell lymphoma and NK/T-cell lymphoma nasal type are rare diseases, colonic involvement has seldom been seen. We report a case of a patient with a primary NK/T-cell lymphoma nasal type of the colon. The patient had no history of malignant diseases and was diagnosed after exhaustive study in the context of fever of unknown origin. The first therapeutic approach followed the DAEPOCH-protocol: etoposide, prednisone, doxor-rubicin, vincristine and cyclophosphamide. The persistence of constitutional symptoms after the first treatment course motivated the switch to a second line following the SMILE-protocol: dexamethasone, metotrexate, ifosfamide, <em>E.coli</em> L-asparaginase, and etoposide. Despite intensive chemotherapy, the patient died 2 months after the diagnose of an extranodal NK/T-cell lymphoma of the colon and 4 months after the first symptomatic appearance of disease. |
| first_indexed | 2024-12-19T03:32:39Z |
| format | Article |
| id | doaj.art-41e66bab4cc046de8fb2a321c26424b3 |
| institution | Directory Open Access Journal |
| issn | 2036-3605 2036-3613 |
| language | English |
| last_indexed | 2024-12-19T03:32:39Z |
| publishDate | 2013-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Rare Tumors |
| spelling | doaj.art-41e66bab4cc046de8fb2a321c26424b32022-12-21T20:37:27ZengSAGE PublishingRare Tumors2036-36052036-36132013-02-0151e9e910.4081/rt.2013.e9Primary NK/T cell lymphoma nasal type of the colonAna María ChirifeJuan Alberto CiccoMarta Elisa ZergaClaudia Érica CasaliMercedes del OlmoMaría de los Ángeles Vicente RepárazGonzalo Martín GarateCarolina Valeria MahuadErica Rojas BilbaoSince nasal NK/T-cell lymphoma and NK/T-cell lymphoma nasal type are rare diseases, colonic involvement has seldom been seen. We report a case of a patient with a primary NK/T-cell lymphoma nasal type of the colon. The patient had no history of malignant diseases and was diagnosed after exhaustive study in the context of fever of unknown origin. The first therapeutic approach followed the DAEPOCH-protocol: etoposide, prednisone, doxor-rubicin, vincristine and cyclophosphamide. The persistence of constitutional symptoms after the first treatment course motivated the switch to a second line following the SMILE-protocol: dexamethasone, metotrexate, ifosfamide, <em>E.coli</em> L-asparaginase, and etoposide. Despite intensive chemotherapy, the patient died 2 months after the diagnose of an extranodal NK/T-cell lymphoma of the colon and 4 months after the first symptomatic appearance of disease.http://www.pagepress.org/journals/index.php/rt/article/view/4606lymphoma, extranodal NK-T-cell, L-asparaginase, intestinal lymphoma |
| spellingShingle | Ana María Chirife Juan Alberto Cicco Marta Elisa Zerga Claudia Érica Casali Mercedes del Olmo María de los Ángeles Vicente Repáraz Gonzalo Martín Garate Carolina Valeria Mahuad Erica Rojas Bilbao Primary NK/T cell lymphoma nasal type of the colon Rare Tumors lymphoma, extranodal NK-T-cell, L-asparaginase, intestinal lymphoma |
| title | Primary NK/T cell lymphoma nasal type of the colon |
| title_full | Primary NK/T cell lymphoma nasal type of the colon |
| title_fullStr | Primary NK/T cell lymphoma nasal type of the colon |
| title_full_unstemmed | Primary NK/T cell lymphoma nasal type of the colon |
| title_short | Primary NK/T cell lymphoma nasal type of the colon |
| title_sort | primary nk t cell lymphoma nasal type of the colon |
| topic | lymphoma, extranodal NK-T-cell, L-asparaginase, intestinal lymphoma |
| url | http://www.pagepress.org/journals/index.php/rt/article/view/4606 |
| work_keys_str_mv | AT anamariachirife primarynktcelllymphomanasaltypeofthecolon AT juanalbertocicco primarynktcelllymphomanasaltypeofthecolon AT martaelisazerga primarynktcelllymphomanasaltypeofthecolon AT claudiaericacasali primarynktcelllymphomanasaltypeofthecolon AT mercedesdelolmo primarynktcelllymphomanasaltypeofthecolon AT mariadelosangelesvicentereparaz primarynktcelllymphomanasaltypeofthecolon AT gonzalomartingarate primarynktcelllymphomanasaltypeofthecolon AT carolinavaleriamahuad primarynktcelllymphomanasaltypeofthecolon AT ericarojasbilbao primarynktcelllymphomanasaltypeofthecolon |