Review: The development of the gastrointestinal tract microbiota and intervention in neonatal ruminants
The complex microbiome colonizing the gastrointestinal tract (GIT) of ruminants plays an important role in the development of the immune system, nutrient absorption and metabolism. Hence, understanding GIT microbiota colonization in neonatal ruminants has positive impacts on host health and producti...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-08-01
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| Series: | Animal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1751731121001592 |
| _version_ | 1819146089713893376 |
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| author | Y. Zhang S.H. Choi K.M. Nogoy S. Liang |
| author_facet | Y. Zhang S.H. Choi K.M. Nogoy S. Liang |
| author_sort | Y. Zhang |
| collection | DOAJ |
| description | The complex microbiome colonizing the gastrointestinal tract (GIT) of ruminants plays an important role in the development of the immune system, nutrient absorption and metabolism. Hence, understanding GIT microbiota colonization in neonatal ruminants has positive impacts on host health and productivity. Microbes rapidly colonize the GIT after birth and gradually develop into a complex microbial community, which allows the possibility of GIT microbiome manipulation to enhance newborn health and growth and perhaps induce lasting effects in adult ruminants. This paper reviews recent advances in understanding how host-microbiome interactions affect the GIT development and health of neonatal ruminants. Following initial GIT microbiome colonization, continuous exposure to host-specific microorganisms is necessary for GIT development and immune system maturation. Furthermore, the early GIT microbial community structure is significantly affected by early life events, such as maternal microbiota exposure, dietary changes, age and the addition of prebiotics, probiotics and synbiotics, supporting the idea of microbial programming in early life. However, the time window in which interventions can optimally improve production and reduce gastrointestinal disease as well as the role of key host-specific microbiota constituents and host immune regulation requires further study. |
| first_indexed | 2024-12-22T13:08:23Z |
| format | Article |
| id | doaj.art-41e74f76311449a39cdbc2450c5be699 |
| institution | Directory Open Access Journal |
| issn | 1751-7311 |
| language | English |
| last_indexed | 2024-12-22T13:08:23Z |
| publishDate | 2021-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Animal |
| spelling | doaj.art-41e74f76311449a39cdbc2450c5be6992022-12-21T18:24:48ZengElsevierAnimal1751-73112021-08-01158100316Review: The development of the gastrointestinal tract microbiota and intervention in neonatal ruminantsY. Zhang0S.H. Choi1K.M. Nogoy2S. Liang3Department of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China; Department of Animal Science, Chungbuk National University, Cheongju 28644, South KoreaDepartment of Animal Science, Chungbuk National University, Cheongju 28644, South KoreaDepartment of Animal Science, Chungbuk National University, Cheongju 28644, South KoreaDepartment of Animal Science, College of Animal Sciences, Jilin University, Changchun 130062, China; Corresponding author.The complex microbiome colonizing the gastrointestinal tract (GIT) of ruminants plays an important role in the development of the immune system, nutrient absorption and metabolism. Hence, understanding GIT microbiota colonization in neonatal ruminants has positive impacts on host health and productivity. Microbes rapidly colonize the GIT after birth and gradually develop into a complex microbial community, which allows the possibility of GIT microbiome manipulation to enhance newborn health and growth and perhaps induce lasting effects in adult ruminants. This paper reviews recent advances in understanding how host-microbiome interactions affect the GIT development and health of neonatal ruminants. Following initial GIT microbiome colonization, continuous exposure to host-specific microorganisms is necessary for GIT development and immune system maturation. Furthermore, the early GIT microbial community structure is significantly affected by early life events, such as maternal microbiota exposure, dietary changes, age and the addition of prebiotics, probiotics and synbiotics, supporting the idea of microbial programming in early life. However, the time window in which interventions can optimally improve production and reduce gastrointestinal disease as well as the role of key host-specific microbiota constituents and host immune regulation requires further study.http://www.sciencedirect.com/science/article/pii/S1751731121001592Early lifeGastrointestinal tract developmentImmune systemMicrobial colonizationRuminants |
| spellingShingle | Y. Zhang S.H. Choi K.M. Nogoy S. Liang Review: The development of the gastrointestinal tract microbiota and intervention in neonatal ruminants Animal Early life Gastrointestinal tract development Immune system Microbial colonization Ruminants |
| title | Review: The development of the gastrointestinal tract microbiota and intervention in neonatal ruminants |
| title_full | Review: The development of the gastrointestinal tract microbiota and intervention in neonatal ruminants |
| title_fullStr | Review: The development of the gastrointestinal tract microbiota and intervention in neonatal ruminants |
| title_full_unstemmed | Review: The development of the gastrointestinal tract microbiota and intervention in neonatal ruminants |
| title_short | Review: The development of the gastrointestinal tract microbiota and intervention in neonatal ruminants |
| title_sort | review the development of the gastrointestinal tract microbiota and intervention in neonatal ruminants |
| topic | Early life Gastrointestinal tract development Immune system Microbial colonization Ruminants |
| url | http://www.sciencedirect.com/science/article/pii/S1751731121001592 |
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