Nuclear DNA-Content in Mesenchymal Lesions in Dogs: Its Value as Marker of Malignancy and Extent of Genomic Instability

Nuclear DNA-Content in Mesenchymal Lesions in Dogs: Its Value as Marker of Malignancy and Extent of Genomic Instability

DNA-aneuploidy may reflect the malignant nature of mesenchymal proliferations and herald gross genomic instability as a mechanistic factor in tumor genesis. DNA-ploidy and -index were determined by flow cytometry in canine inflammatory or neoplastic mesenchymal tissues and related to clinico-patholo...

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Bibliographic Details
Main Authors: Christoph Schulze, Guy C. M. Grinwis, Jolle Kirpensteijn, Marja J. L. Kik, Gerard R. Rutteman, Kim M. Boerkamp
Format: Article
Language:English
Published: MDPI AG 2012-12-01
Series:Cancers
Subjects:
aneuploidy evolution
canine
sarcomas
DNA index
Online Access:http://www.mdpi.com/2072-6694/4/4/1300

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http://www.mdpi.com/2072-6694/4/4/1300

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