Neuromedin U signaling regulates retrieval of learned salt avoidance in a C. elegans gustatory circuit

Learning and memory are regulated by neuropeptides. Here, the authors show that the neuropeptide CAPA-1 and its receptor NMUR-1 are required to retrieve learned salt avoidance in C. elegans. CAPA-1/NMUR-1 activation in AFD sensory neurons modulates locomotor programs to express learned avoidance.

Bibliographic Details
Main Authors: Jan Watteyne, Katleen Peymen, Petrus Van der Auwera, Charline Borghgraef, Elke Vandewyer, Sara Van Damme, Iene Rutten, Jeroen Lammertyn, Rob Jelier, Liliane Schoofs, Isabel Beets
Format: Article
Language:English
Published: Nature Portfolio 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15964-9

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