Hematopoietic Dysfunction during Graft-Versus-Host Disease: A Self-Destructive Process?

Hematopoietic Dysfunction during Graft-Versus-Host Disease: A Self-Destructive Process?

Graft-versus-host disease (GvHD) is a major complication of allogeneic hematopoietic (stem) cell transplantation (HCT). Clinically, GvHD is associated with severe and long-lasting hematopoietic dysfunction, which may contribute to the high mortality of GvHD after HCT. During GvHD, excessive immune a...

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Bibliographic Details
Main Authors: Konradin F. Müskens, Caroline A. Lindemans, Mirjam E. Belderbos
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
hematopoietic stem cell transplantation
graft-versus-host disease
hematopoiesis
bone marrow niche
cytopenia
poor graft function
Online Access:https://www.mdpi.com/2073-4409/10/8/2051

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