Efficacy of platelet-rich plasma lysate in the treatment of patients with post-traumatic eyelid scarring: an overview of clinical cases
Purpose: to evaluate the effectiveness of platelet-rich plasma lysate (PRP) in the treatment of patients with post-traumatic eyelid scarring by clinical examples. Material and methods. Patients with post-traumatic scarring changes in eyelid tissues causing a damage in the functional and cosmetic sta...
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| Format: | Article |
| Language: | Russian |
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Real Time Ltd
2022-01-01
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| Series: | Российский офтальмологический журнал |
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| Online Access: | https://roj.igb.ru/jour/article/view/788 |
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| author | I. A. Filatova Yu. A. Pavlenko S. A. Shemetov E. V. Fedoseeva I. N. Ponomarev N. V. Borovkova |
| author_facet | I. A. Filatova Yu. A. Pavlenko S. A. Shemetov E. V. Fedoseeva I. N. Ponomarev N. V. Borovkova |
| author_sort | I. A. Filatova |
| collection | DOAJ |
| description | Purpose: to evaluate the effectiveness of platelet-rich plasma lysate (PRP) in the treatment of patients with post-traumatic eyelid scarring by clinical examples. Material and methods. Patients with post-traumatic scarring changes in eyelid tissues causing a damage in the functional and cosmetic state of the auxiliary apparatus of the eye were treated in the Department of Plastic Surgery and Eye Prosthetics at the Helmholtz National Medical Research Center of Eye Diseases. Two of the patients, who had been traumatized shortly before the examination and one patient who had rejected surgery were offered treatment by PRP lysate manufactured at the Sklifosovsky Medical Research Institute of Emergency Medicine. After local infiltration anesthesia, each patient received a single injection of PRP lysate (2 ml) into the scar tissue. The result was evaluated at a follow-up that took place 3 months after the injection. Results. The clinical picture of the three patients showed a pronounced positive dynamic of the functional and cosmetic state of the auxiliary eye apparatus, which made the patients reject subsequent (additional) surgical treatment. Conclusion. An improvement tissue repair and regeneration processes after PRP lysate injection allows us to assess this method as an applicable alternative of reconstructive operations in certain cases. |
| first_indexed | 2024-04-10T02:30:12Z |
| format | Article |
| id | doaj.art-41f988b36bcd46a1ac7a86d0088bb7c3 |
| institution | Directory Open Access Journal |
| issn | 2072-0076 2587-5760 |
| language | Russian |
| last_indexed | 2025-03-14T11:46:03Z |
| publishDate | 2022-01-01 |
| publisher | Real Time Ltd |
| record_format | Article |
| series | Российский офтальмологический журнал |
| spelling | doaj.art-41f988b36bcd46a1ac7a86d0088bb7c32025-03-02T09:51:28ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602022-01-01144222610.21516/2072-0076-2021-14-4-supplement-22-26402Efficacy of platelet-rich plasma lysate in the treatment of patients with post-traumatic eyelid scarring: an overview of clinical casesI. A. Filatova0Yu. A. Pavlenko1S. A. Shemetov2E. V. Fedoseeva3I. N. Ponomarev4N. V. Borovkova5Helmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency MedicinePurpose: to evaluate the effectiveness of platelet-rich plasma lysate (PRP) in the treatment of patients with post-traumatic eyelid scarring by clinical examples. Material and methods. Patients with post-traumatic scarring changes in eyelid tissues causing a damage in the functional and cosmetic state of the auxiliary apparatus of the eye were treated in the Department of Plastic Surgery and Eye Prosthetics at the Helmholtz National Medical Research Center of Eye Diseases. Two of the patients, who had been traumatized shortly before the examination and one patient who had rejected surgery were offered treatment by PRP lysate manufactured at the Sklifosovsky Medical Research Institute of Emergency Medicine. After local infiltration anesthesia, each patient received a single injection of PRP lysate (2 ml) into the scar tissue. The result was evaluated at a follow-up that took place 3 months after the injection. Results. The clinical picture of the three patients showed a pronounced positive dynamic of the functional and cosmetic state of the auxiliary eye apparatus, which made the patients reject subsequent (additional) surgical treatment. Conclusion. An improvement tissue repair and regeneration processes after PRP lysate injection allows us to assess this method as an applicable alternative of reconstructive operations in certain cases.https://roj.igb.ru/jour/article/view/788post-traumatic scareyelid scarringplateletsplatelet-rich plasma lysateautologous plasma |
| spellingShingle | I. A. Filatova Yu. A. Pavlenko S. A. Shemetov E. V. Fedoseeva I. N. Ponomarev N. V. Borovkova Efficacy of platelet-rich plasma lysate in the treatment of patients with post-traumatic eyelid scarring: an overview of clinical cases Российский офтальмологический журнал post-traumatic scar eyelid scarring platelets platelet-rich plasma lysate autologous plasma |
| title | Efficacy of platelet-rich plasma lysate in the treatment of patients with post-traumatic eyelid scarring: an overview of clinical cases |
| title_full | Efficacy of platelet-rich plasma lysate in the treatment of patients with post-traumatic eyelid scarring: an overview of clinical cases |
| title_fullStr | Efficacy of platelet-rich plasma lysate in the treatment of patients with post-traumatic eyelid scarring: an overview of clinical cases |
| title_full_unstemmed | Efficacy of platelet-rich plasma lysate in the treatment of patients with post-traumatic eyelid scarring: an overview of clinical cases |
| title_short | Efficacy of platelet-rich plasma lysate in the treatment of patients with post-traumatic eyelid scarring: an overview of clinical cases |
| title_sort | efficacy of platelet rich plasma lysate in the treatment of patients with post traumatic eyelid scarring an overview of clinical cases |
| topic | post-traumatic scar eyelid scarring platelets platelet-rich plasma lysate autologous plasma |
| url | https://roj.igb.ru/jour/article/view/788 |
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