Aluminum-induced amyloidogenesis and impairment in the clearance of amyloid peptides from the central nervous system (CNS) in Alzheimer’s disease (AD)

Aluminum-induced amyloidogenesis and impairment in the clearance of amyloid peptides from the central nervous system (CNS) in Alzheimer’s disease (AD)

Bibliographic Details
Main Authors:	Yuhai eZhao, James M Hill, Surjyadipta eBhattacharjee, Maire E. Percy, Aileen I.D. Pogue, Walter J Lukiw
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2014-09-01
Series:	Frontiers in Neurology
Subjects:	Aluminum Phagocytosis Alzheimer's disease amyloidogenesis TREM2 Aβ42 peptide monomers
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fneur.2014.00167/full

Similar Items

Regulating amyloidogenesis through the natural triggering receptor expressed in myeloid/microglial cells 2 (TREM2)
by: Brandon M Jones, et al.
Published: (2014-03-01)

Deficits in the miRNA-34a-regulated endogenous TREM2 phagocytosis sensor-receptor in Alzheimer’s disease (AD); an update
by: Surjyadipta eBhattacharjee, et al.
Published: (2014-06-01)

Review on the Structures and Activities of Transthyretin Amyloidogenesis Inhibitors
by: Guo X, et al.
Published: (2020-03-01)

TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance
by: Xianyuan Xiang, et al.
Published: (2016-09-01)

Pharmacophore-based design and discovery of (−)-meptazinol carbamates as dual modulators of cholinesterase and amyloidogenesis
by: Qiong Xie, et al.
Published: (2017-01-01)

Historical and Current Concepts of Fibrillogenesis and In Vivo Amyloidogenesis: Implications of Amyloid Tissue Targeting
by: Robert eKisilevsky, et al.
Published: (2016-05-01)

Amyloidogenesis and Neurotrophic Dysfunction in Alzheimer’s Disease: Do They have a Common Regulating Pathway?
by: Fengjuan Jiao, et al.
Published: (2022-10-01)

Monitoring amyloidogenesis with a 3D deep-learning-guided biolaser imaging array
by: Chan, Kok Ken, et al.
Published: (2023)

AL(light chain)-amyloidogenesis by mesangial cells involves active participation of lysosomes: An ultrastructural study
by: Guillermo A. Herrera, et al.
Published: (2023-04-01)

DEAD-Box Helicase 17 Promotes Amyloidogenesis by Regulating BACE1 Translation
by: Yue Liu, et al.
Published: (2023-04-01)

Aluminum and its potential contribution to Alzheimer’s disease (AD)
by: Surjyadipta eBhattacharjee, et al.
Published: (2014-04-01)

Phytochemical Interactions with Calmodulin and Critical Calmodulin Binding Proteins Involved in Amyloidogenesis in Alzheimer’s Disease
by: Danton H. O'Day
Published: (2023-04-01)

VEGF controls microglial phagocytic response to amyloid-β
by: Priscille de Gea, et al.
Published: (2023-12-01)

Pathogenic microbes, the microbiome, and Alzheimer's disease (AD)
by: James M Hill, et al.
Published: (2014-06-01)

Cannabidiol Enhances Microglial Beta-Amyloid Peptide Phagocytosis and Clearance via Vanilloid Family Type 2 Channel Activation
by: Shaobin Yang, et al.
Published: (2022-05-01)

3-O-Methyltolcapone and Its Lipophilic Analogues Are Potent Inhibitors of Transthyretin Amyloidogenesis with High Permeability and Low Toxicity
by: Thanalai Poonsiri, et al.
Published: (2023-12-01)

TREM2 Expression and Amyloid-Beta Phagocytosis in Alzheimer’s Disease
by: Francesca La Rosa, et al.
Published: (2023-05-01)

Regulation of microglia phagocytosis and potential involvement of exercise
by: Congqin Li, et al.
Published: (2022-07-01)

miRNAs and viroids utilize common strategies in genetic signal transfer
by: James M Hill, et al.
Published: (2014-02-01)

Bee venom phospholipase A2 ameliorates amyloidogenesis and neuroinflammation through inhibition of signal transducer and activator of transcription-3 pathway in Tg2576 mice
by: Hyeon Joo Ham, et al.
Published: (2019-10-01)

The gastrointestinal (GI) tract microbiome and potential link to Alzheimer’s disease (AD)
by: James M. Hill, et al.
Published: (2014-04-01)

Cholesterol-dependent amyloid β production: space for multifarious interactions between amyloid precursor protein, secretases, and cholesterol
by: Vladimir Rudajev, et al.
Published: (2023-09-01)

Genetic models of cleavage-reduced and soluble TREM2 reveal distinct effects on myelination and microglia function in the cuprizone model
by: Nicolau Beckmann, et al.
Published: (2023-02-01)

The Emerging Role of Triggering Receptor Expressed on Myeloid Cells 2 as a Target for Immunomodulation in Ischemic Stroke
by: Pascal Gervois, et al.
Published: (2019-07-01)

TREM2 signaling, miRNA-34a and the extinction of phagocytosis
by: Yuhai eZhao, et al.
Published: (2013-08-01)

Amyloids: The History of Toxicity and Functionality
by: Elmira I. Yakupova, et al.
Published: (2021-05-01)

Alzheimer’s disease and the microbiome
by: Surjyadipta eBhattacharjee, et al.
Published: (2013-09-01)

Paeonol enhances macrophage phagocytic function by modulating lipid metabolism through the P53-TREM2 axis
by: Jifei Miao, et al.
Published: (2023-06-01)

Sphingosine-1-phosphate, a novel TREM2 ligand, promotes microglial phagocytosis to protect against ischemic brain injury
by: Tengfei Xue, et al.
Published: (2022-04-01)

Therapeutic Trem2 activation ameliorates amyloid-beta deposition and improves cognition in the 5XFAD model of amyloid deposition
by: Brittani R. Price, et al.
Published: (2020-08-01)

Relationship between Changes in the Protein Folding Pathway and the Process of Amyloid Formation: The Case of Bovine Carbonic Anhydrase II
by: Bogdan S. Melnik, et al.
Published: (2022-11-01)

Distinct Signaling Pathways Regulate TREM2 Phagocytic and NFκB Antagonistic Activities
by: Hailan Yao, et al.
Published: (2019-10-01)

Switching On/Off Amyloid Plaque Formation in Transgenic Animal Models of Alzheimer’s Disease
by: Sergey A. Kozin, et al.
Published: (2023-12-01)

Studying micro RNA (miRNA) function and dysfunction in Alzheimer’s disease
by: Walter J Lukiw, et al.
Published: (2013-02-01)

Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD mice
by: Peng Zhao, et al.
Published: (2022-12-01)

Curcumin restores innate immune Alzheimer's disease risk gene expression to ameliorate Alzheimer pathogenesis
by: B. Teter, et al.
Published: (2019-07-01)

Transmissible Endosomal Intoxication: A Balance between Exosomes and Lysosomes at the Basis of Intercellular Amyloid Propagation
by: Anaïs Bécot, et al.
Published: (2020-08-01)

Synthetic, Cell-Derived, Brain-Derived, and Recombinant β-Amyloid: Modelling Alzheimer’s Disease for Research and Drug Development
by: Kseniya B. Varshavskaya, et al.
Published: (2022-11-01)

Anesthesia and surgery-induced elevation of CSF sTREM2 is associated with early cognitive dysfunction after thoracoabdominal aortic dissection surgery
by: Kexin Wang, et al.
Published: (2022-12-01)

Fluorescence-Labeled Amyloid Beta Monomer: A Molecular Dynamical Study
by: János Gera, et al.
Published: (2020-08-01)