Patient-derived scaffolds representing breast cancer microenvironments influence chemotherapy responses in adapted cancer cells consistent with clinical features

Patient-derived scaffolds representing breast cancer microenvironments influence chemotherapy responses in adapted cancer cells consistent with clinical features

Abstract Background The tumor microenvironment clearly influences cancer progressing properties but less is known about how individual cancer microenvironments potentially moderate cancer treatment effects. By cultivating and treating cancer cell lines in patient-derived scaffolds (PDS), the impact...

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Bibliographic Details
Main Authors:	Maria Carmen Leiva, Anna Gustafsson, Elena Garre, Anders Ståhlberg, Anikó Kovács, Khalil Helou, Göran Landberg
Format:	Article
Language:	English
Published:	BMC 2023-12-01
Series:	Journal of Translational Medicine
Subjects:	Breast cancer Patient-derived scaffolds Cancer microenvironment Chemotherapy Doxorubicin 5-Fluorouracil
Online Access:	https://doi.org/10.1186/s12967-023-04806-z

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