Aberrant activation of the human sex-determining gene in early embryonic development results in postnatal growth retardation and lethality in mice

Aberrant activation of the human sex-determining gene in early embryonic development results in postnatal growth retardation and lethality in mice

Abstract Sexual dimorphisms are prevalent in development, physiology and diseases in humans. Currently, the contributions of the genes on the male-specific region of the Y chromosome (MSY) in these processes are uncertain. Using a transgene activation system, the human sex-determining gene hSRY is a...

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Bibliographic Details
Main Authors:	Tatsuo Kido, Zhaoyu Sun, Yun-Fai Chris Lau
Format:	Article
Language:	English
Published:	Nature Portfolio 2017-06-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-017-04117-6

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