Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community
Background: World Health Organization (WHO) data collection of Escherichia coli resistant to cephalosporin generation III already confirmed in 86 countries. Incredibly high carrier prevalence rates were also widely developed in Thailand, Egypt, and China. The Faculty of Medicine's research team...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
Diponegoro University
2021-04-01
|
Series: | Journal of Biomedicine and Translational Research |
Subjects: | |
Online Access: | https://ejournal2.undip.ac.id/index.php/jbtr/article/view/10051 |
_version_ | 1818900212654014464 |
---|---|
author | Nia Krisniawati Anriani Puspita Karunia Ning Widhi |
author_facet | Nia Krisniawati Anriani Puspita Karunia Ning Widhi |
author_sort | Nia Krisniawati |
collection | DOAJ |
description | Background: World Health Organization (WHO) data collection of Escherichia coli resistant to cephalosporin generation III already confirmed in 86 countries. Incredibly high carrier prevalence rates were also widely developed in Thailand, Egypt, and China. The Faculty of Medicine's research team at Jenderal Soedirman University, Purwokerto, discovered at the beginning of 2018 that Extended Spectrum β-Lactamase (ESBL) E. coli carriers throughout the 2015 class students were 26.8 percent.
Objective: This research investigated the Prevalence and associated factors of ESBL-producing Enterobacteriaceae (EPE) asymptomatic carriers in the community.
Methods: The participant fill a questionnaire, and samples were taken from rectal swabs using Amies transport medium (Labware Charuzu), and then models were analyze using HiCrome ™ ESBL Agar Base (Himedia, India). Analysis of its Prevalence and Resistance Predictors uses IBM SPSS Statistics Version 22.0 for Windows (Armonk, NY: IBM Corp).
Results: The Prevalence of EPE asymptomatic carriers in the community in Purwokerto was 66.7%. In the bivariate analysis, subjects who took antacids in the last eight weeks, history of hospitalization in the previous 12 months, the habit of consuming milk, yogurt, cheese, meat, seafood, and raw vegetables did not show any significant difference. Frequent chicken and freshwater fish consumption tended to be a risk factor for ESBL-producing Enterobacteriaceae with PR 1.462, 95% CI (1.115-1.918); PR 1.666, 95% CI (0.936-2.966); however, in the multivariate logistic regression analysis, this was not significant.
Conclusion: The Prevalence of EPE asymptomatic carriers in the community in Purwokerto is 66.7%. All variables did not become any significant of ESBL-producing Enterobacteriaceae. However, ESBL remains an emerging antimicrobial resistance. |
first_indexed | 2024-12-19T20:00:16Z |
format | Article |
id | doaj.art-42012ac42b7e4dc98d64f240ee10c0f9 |
institution | Directory Open Access Journal |
issn | 2503-2178 |
language | English |
last_indexed | 2024-12-19T20:00:16Z |
publishDate | 2021-04-01 |
publisher | Diponegoro University |
record_format | Article |
series | Journal of Biomedicine and Translational Research |
spelling | doaj.art-42012ac42b7e4dc98d64f240ee10c0f92022-12-21T20:07:41ZengDiponegoro UniversityJournal of Biomedicine and Translational Research2503-21782021-04-01711610.14710/jbtr.v7i1.100514849Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The CommunityNia Krisniawati0Anriani Puspita Karunia Ning Widhi1Faculty of Medicine, Universitas Jenderal Soedirman, IndonesiaFaculty of Medicine, Universitas Jenderal Soedirman, IndonesiaBackground: World Health Organization (WHO) data collection of Escherichia coli resistant to cephalosporin generation III already confirmed in 86 countries. Incredibly high carrier prevalence rates were also widely developed in Thailand, Egypt, and China. The Faculty of Medicine's research team at Jenderal Soedirman University, Purwokerto, discovered at the beginning of 2018 that Extended Spectrum β-Lactamase (ESBL) E. coli carriers throughout the 2015 class students were 26.8 percent. Objective: This research investigated the Prevalence and associated factors of ESBL-producing Enterobacteriaceae (EPE) asymptomatic carriers in the community. Methods: The participant fill a questionnaire, and samples were taken from rectal swabs using Amies transport medium (Labware Charuzu), and then models were analyze using HiCrome ™ ESBL Agar Base (Himedia, India). Analysis of its Prevalence and Resistance Predictors uses IBM SPSS Statistics Version 22.0 for Windows (Armonk, NY: IBM Corp). Results: The Prevalence of EPE asymptomatic carriers in the community in Purwokerto was 66.7%. In the bivariate analysis, subjects who took antacids in the last eight weeks, history of hospitalization in the previous 12 months, the habit of consuming milk, yogurt, cheese, meat, seafood, and raw vegetables did not show any significant difference. Frequent chicken and freshwater fish consumption tended to be a risk factor for ESBL-producing Enterobacteriaceae with PR 1.462, 95% CI (1.115-1.918); PR 1.666, 95% CI (0.936-2.966); however, in the multivariate logistic regression analysis, this was not significant. Conclusion: The Prevalence of EPE asymptomatic carriers in the community in Purwokerto is 66.7%. All variables did not become any significant of ESBL-producing Enterobacteriaceae. However, ESBL remains an emerging antimicrobial resistance.https://ejournal2.undip.ac.id/index.php/jbtr/article/view/10051carrierresistancerisk factorsenterobacteriaceaeesbl |
spellingShingle | Nia Krisniawati Anriani Puspita Karunia Ning Widhi Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community Journal of Biomedicine and Translational Research carrier resistance risk factors enterobacteriaceae esbl |
title | Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community |
title_full | Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community |
title_fullStr | Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community |
title_full_unstemmed | Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community |
title_short | Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community |
title_sort | prevalence and risk factors of esbl producing enterobacteriaceae in the community |
topic | carrier resistance risk factors enterobacteriaceae esbl |
url | https://ejournal2.undip.ac.id/index.php/jbtr/article/view/10051 |
work_keys_str_mv | AT niakrisniawati prevalenceandriskfactorsofesblproducingenterobacteriaceaeinthecommunity AT anrianipuspitakarunianingwidhi prevalenceandriskfactorsofesblproducingenterobacteriaceaeinthecommunity |