Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community

Background: World Health Organization (WHO) data collection of Escherichia coli resistant to cephalosporin generation III already confirmed in 86 countries. Incredibly high carrier prevalence rates were also widely developed in Thailand, Egypt, and China. The Faculty of Medicine's research team...

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Main Authors: Nia Krisniawati, Anriani Puspita Karunia Ning Widhi
Format: Article
Language:English
Published: Diponegoro University 2021-04-01
Series:Journal of Biomedicine and Translational Research
Subjects:
Online Access:https://ejournal2.undip.ac.id/index.php/jbtr/article/view/10051
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author Nia Krisniawati
Anriani Puspita Karunia Ning Widhi
author_facet Nia Krisniawati
Anriani Puspita Karunia Ning Widhi
author_sort Nia Krisniawati
collection DOAJ
description Background: World Health Organization (WHO) data collection of Escherichia coli resistant to cephalosporin generation III already confirmed in 86 countries. Incredibly high carrier prevalence rates were also widely developed in Thailand, Egypt, and China. The Faculty of Medicine's research team at Jenderal Soedirman University, Purwokerto,  discovered at the beginning of 2018 that Extended Spectrum β-Lactamase (ESBL) E. coli carriers throughout the 2015 class students were 26.8 percent. Objective: This research investigated the Prevalence and associated factors of ESBL-producing Enterobacteriaceae (EPE) asymptomatic carriers in the community. Methods: The participant fill a questionnaire, and samples were taken from rectal swabs using Amies transport medium (Labware Charuzu), and then models were analyze using HiCrome ™ ESBL Agar Base (Himedia, India). Analysis of its Prevalence and Resistance Predictors uses IBM SPSS Statistics Version 22.0 for Windows (Armonk, NY: IBM Corp). Results: The Prevalence of EPE asymptomatic carriers in the community in Purwokerto was 66.7%. In the bivariate analysis, subjects who took antacids in the last eight weeks, history of hospitalization in the previous 12 months, the habit of consuming milk, yogurt, cheese, meat, seafood, and raw vegetables did not show any significant difference. Frequent chicken and freshwater fish consumption tended to be a risk factor for ESBL-producing Enterobacteriaceae with PR 1.462, 95% CI (1.115-1.918); PR 1.666, 95% CI  (0.936-2.966); however, in the multivariate logistic regression analysis, this was not significant. Conclusion: The Prevalence of EPE asymptomatic carriers in the community in Purwokerto is 66.7%. All variables did not become any significant of ESBL-producing Enterobacteriaceae. However, ESBL remains an emerging antimicrobial resistance.
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spelling doaj.art-42012ac42b7e4dc98d64f240ee10c0f92022-12-21T20:07:41ZengDiponegoro UniversityJournal of Biomedicine and Translational Research2503-21782021-04-01711610.14710/jbtr.v7i1.100514849Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The CommunityNia Krisniawati0Anriani Puspita Karunia Ning Widhi1Faculty of Medicine, Universitas Jenderal Soedirman, IndonesiaFaculty of Medicine, Universitas Jenderal Soedirman, IndonesiaBackground: World Health Organization (WHO) data collection of Escherichia coli resistant to cephalosporin generation III already confirmed in 86 countries. Incredibly high carrier prevalence rates were also widely developed in Thailand, Egypt, and China. The Faculty of Medicine's research team at Jenderal Soedirman University, Purwokerto,  discovered at the beginning of 2018 that Extended Spectrum β-Lactamase (ESBL) E. coli carriers throughout the 2015 class students were 26.8 percent. Objective: This research investigated the Prevalence and associated factors of ESBL-producing Enterobacteriaceae (EPE) asymptomatic carriers in the community. Methods: The participant fill a questionnaire, and samples were taken from rectal swabs using Amies transport medium (Labware Charuzu), and then models were analyze using HiCrome ™ ESBL Agar Base (Himedia, India). Analysis of its Prevalence and Resistance Predictors uses IBM SPSS Statistics Version 22.0 for Windows (Armonk, NY: IBM Corp). Results: The Prevalence of EPE asymptomatic carriers in the community in Purwokerto was 66.7%. In the bivariate analysis, subjects who took antacids in the last eight weeks, history of hospitalization in the previous 12 months, the habit of consuming milk, yogurt, cheese, meat, seafood, and raw vegetables did not show any significant difference. Frequent chicken and freshwater fish consumption tended to be a risk factor for ESBL-producing Enterobacteriaceae with PR 1.462, 95% CI (1.115-1.918); PR 1.666, 95% CI  (0.936-2.966); however, in the multivariate logistic regression analysis, this was not significant. Conclusion: The Prevalence of EPE asymptomatic carriers in the community in Purwokerto is 66.7%. All variables did not become any significant of ESBL-producing Enterobacteriaceae. However, ESBL remains an emerging antimicrobial resistance.https://ejournal2.undip.ac.id/index.php/jbtr/article/view/10051carrierresistancerisk factorsenterobacteriaceaeesbl
spellingShingle Nia Krisniawati
Anriani Puspita Karunia Ning Widhi
Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community
Journal of Biomedicine and Translational Research
carrier
resistance
risk factors
enterobacteriaceae
esbl
title Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community
title_full Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community
title_fullStr Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community
title_full_unstemmed Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community
title_short Prevalence and Risk Factors of ESBL-producing Enterobacteriaceae in The Community
title_sort prevalence and risk factors of esbl producing enterobacteriaceae in the community
topic carrier
resistance
risk factors
enterobacteriaceae
esbl
url https://ejournal2.undip.ac.id/index.php/jbtr/article/view/10051
work_keys_str_mv AT niakrisniawati prevalenceandriskfactorsofesblproducingenterobacteriaceaeinthecommunity
AT anrianipuspitakarunianingwidhi prevalenceandriskfactorsofesblproducingenterobacteriaceaeinthecommunity