Optimisation of an Electrochemical DNA Sensor for Measuring KRAS G12D and G13D Point Mutations in Different Tumour Types

Optimisation of an Electrochemical DNA Sensor for Measuring KRAS G12D and G13D Point Mutations in Different Tumour Types

Circulating tumour DNA (ctDNA) is widely used in liquid biopsies due to having a presence in the blood that is typically in proportion to the stage of the cancer and because it may present a quick and practical method of capturing tumour heterogeneity. This paper outlines a simple electrochemical te...

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Bibliographic Details
Main Authors: Bukola Attoye, Matthew J. Baker, Fiona Thomson, Chantevy Pou, Damion K. Corrigan
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Biosensors
Subjects:
electrochemical
DNA biosensors
KRAS
liquid biopsy
cancer point-of-care diagnostic tests
Online Access:https://www.mdpi.com/2079-6374/11/2/42

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