Patogenesi ed epidemiologia dei tumori associati all’infezione da virus di Epstein-Barr
The Epstein-Barr virus (EBV) is one of the most successful human viruses: it is ubiquitous worldwide, and more than 80% of people over the age of 30 show serological evidence of infection. In addition, EBV infection tends to be persistent, so that, once it has occurred, it remains for the lifetime,...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2006-03-01
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| Series: | Microbiologia Medica |
| Subjects: | |
| Online Access: | http://www.pagepressjournals.org/index.php/mm/article/view/2947 |
| _version_ | 1818444596751892480 |
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| author | Maria Rosaria Sciarrone Pierluca Piselli Stefania Bellelli Lucia Fratino Giuseppe Ippolito Maria Rosaria Capobianchi Diego Serraino |
| author_facet | Maria Rosaria Sciarrone Pierluca Piselli Stefania Bellelli Lucia Fratino Giuseppe Ippolito Maria Rosaria Capobianchi Diego Serraino |
| author_sort | Maria Rosaria Sciarrone |
| collection | DOAJ |
| description | The Epstein-Barr virus (EBV) is one of the most successful human viruses: it is ubiquitous worldwide, and more than 80% of people over the age of 30 show serological evidence of infection. In addition, EBV infection tends to be persistent, so that, once it has occurred, it remains for the lifetime, a feature that is common to many other herpesviral infections. EBV is strongly associated with the development of several cancers, in particular with Burkitt’s lymphoma, Hodgkin’s disease, and lymphoproliferative disorders which complicate immune suppression conditions. These EBV-associated neoplasms are characterized by peculiar geographic distributions and distinctive epidemiologic features.This review refers to recent advances in the mechanisms of EBV-induced cell transformation, and is focused on the main epidemiological aspects of virus-associated malignancies. |
| first_indexed | 2024-12-14T19:18:27Z |
| format | Article |
| id | doaj.art-42055d2e57cc4c8796e17e773117e313 |
| institution | Directory Open Access Journal |
| issn | 2280-6423 |
| language | English |
| last_indexed | 2024-12-14T19:18:27Z |
| publishDate | 2006-03-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Microbiologia Medica |
| spelling | doaj.art-42055d2e57cc4c8796e17e773117e3132022-12-21T22:50:26ZengPAGEPress PublicationsMicrobiologia Medica2280-64232006-03-0121110.4081/mm.2006.29472193Patogenesi ed epidemiologia dei tumori associati all’infezione da virus di Epstein-BarrMaria Rosaria SciarronePierluca PiselliStefania BellelliLucia FratinoGiuseppe IppolitoMaria Rosaria CapobianchiDiego SerrainoThe Epstein-Barr virus (EBV) is one of the most successful human viruses: it is ubiquitous worldwide, and more than 80% of people over the age of 30 show serological evidence of infection. In addition, EBV infection tends to be persistent, so that, once it has occurred, it remains for the lifetime, a feature that is common to many other herpesviral infections. EBV is strongly associated with the development of several cancers, in particular with Burkitt’s lymphoma, Hodgkin’s disease, and lymphoproliferative disorders which complicate immune suppression conditions. These EBV-associated neoplasms are characterized by peculiar geographic distributions and distinctive epidemiologic features.This review refers to recent advances in the mechanisms of EBV-induced cell transformation, and is focused on the main epidemiological aspects of virus-associated malignancies.http://www.pagepressjournals.org/index.php/mm/article/view/2947EBV, latenza, tumori |
| spellingShingle | Maria Rosaria Sciarrone Pierluca Piselli Stefania Bellelli Lucia Fratino Giuseppe Ippolito Maria Rosaria Capobianchi Diego Serraino Patogenesi ed epidemiologia dei tumori associati all’infezione da virus di Epstein-Barr Microbiologia Medica EBV, latenza, tumori |
| title | Patogenesi ed epidemiologia dei tumori associati all’infezione da virus di Epstein-Barr |
| title_full | Patogenesi ed epidemiologia dei tumori associati all’infezione da virus di Epstein-Barr |
| title_fullStr | Patogenesi ed epidemiologia dei tumori associati all’infezione da virus di Epstein-Barr |
| title_full_unstemmed | Patogenesi ed epidemiologia dei tumori associati all’infezione da virus di Epstein-Barr |
| title_short | Patogenesi ed epidemiologia dei tumori associati all’infezione da virus di Epstein-Barr |
| title_sort | patogenesi ed epidemiologia dei tumori associati all infezione da virus di epstein barr |
| topic | EBV, latenza, tumori |
| url | http://www.pagepressjournals.org/index.php/mm/article/view/2947 |
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