Malaria in Indonesia: current treatment approaches, future strategies, and potential herbal interventions
Malaria remains a significant public health challenge in Indonesia, with varying prevalence across regions, particularly in eastern provinces like Papua and West Papua. This parasitic disease, transmitted by Plasmodium-infected Anopheles mosquitoes, continues to burden affected populations. Contempo...
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| Format: | Article |
| Language: | English |
| Published: |
Pensoft Publishers
2024-02-01
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| Series: | Pharmacia |
| Online Access: | https://pharmacia.pensoft.net/article/116095/download/pdf/ |
| _version_ | 1797304127913459712 |
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| author | Tina Christina L. Tobing Wahrianto Eka Saputri Nasywa Inayah Wafa Putri Daffa Zulfianti Lidwina Iswari Sihaloho Annisa Rabbiatul Husna Devia Salsabila Fito Hansen Hotasi Silalahi Alex Insandus Sitohang Aysiah Sabrina Atika Darayani Hasyati Harianja Silvyani Agustilova Barus Salwa Sabina Annisa Aulia Rahma Adrian Joshua Velaro Khairunnisa Khairunnnisa Emil Salim Fahrul Nurkolis Rony Abdi Syahputra |
| author_facet | Tina Christina L. Tobing Wahrianto Eka Saputri Nasywa Inayah Wafa Putri Daffa Zulfianti Lidwina Iswari Sihaloho Annisa Rabbiatul Husna Devia Salsabila Fito Hansen Hotasi Silalahi Alex Insandus Sitohang Aysiah Sabrina Atika Darayani Hasyati Harianja Silvyani Agustilova Barus Salwa Sabina Annisa Aulia Rahma Adrian Joshua Velaro Khairunnisa Khairunnnisa Emil Salim Fahrul Nurkolis Rony Abdi Syahputra |
| author_sort | Tina Christina L. Tobing |
| collection | DOAJ |
| description | Malaria remains a significant public health challenge in Indonesia, with varying prevalence across regions, particularly in eastern provinces like Papua and West Papua. This parasitic disease, transmitted by Plasmodium-infected Anopheles mosquitoes, continues to burden affected populations. Contemporary treatment approaches predominantly rely on Artemisinin-based Combination Therapy (ACT). However, the emergence of drug resistance, coupled with environmental and demographic factors, presents ongoing challenges. This paper explores current malaria treatment strategies in Indonesia, emphasizing the importance of vigilance in the face of drug resistance and the need for innovative approaches. Additionally, it discusses the potential of herbal interventions, drawing from the rich traditional knowledge of medicinal plants in Indonesia. Secondary metabolites found in herbs, including flavonoids, terpenoids, and alkaloids, show promise as antimalarial agents. As Indonesia and the global community strive to combat malaria, research, surveillance, and healthcare infrastructure development must remain at the forefront of strategies. Despite the complex nature of malaria control, continued dedication and collaboration offer hope for reducing the disease’s impact and progressing towards its eventual elimination. Graphical abstract: |
| first_indexed | 2024-03-08T00:03:56Z |
| format | Article |
| id | doaj.art-42196cb192f74f328c49baaf33bc28ca |
| institution | Directory Open Access Journal |
| issn | 2603-557X |
| language | English |
| last_indexed | 2024-03-08T00:03:56Z |
| publishDate | 2024-02-01 |
| publisher | Pensoft Publishers |
| record_format | Article |
| series | Pharmacia |
| spelling | doaj.art-42196cb192f74f328c49baaf33bc28ca2024-02-17T10:40:38ZengPensoft PublishersPharmacia2603-557X2024-02-017111410.3897/pharmacia.71.e116095116095Malaria in Indonesia: current treatment approaches, future strategies, and potential herbal interventionsTina Christina L. Tobing0Wahrianto1Eka Saputri2Nasywa Inayah Wafa3Putri Daffa Zulfianti4Lidwina Iswari Sihaloho5Annisa Rabbiatul Husna6Devia Salsabila7Fito Hansen Hotasi Silalahi8Alex Insandus Sitohang9Aysiah Sabrina10Atika Darayani Hasyati Harianja11Silvyani Agustilova Barus12Salwa Sabina13Annisa Aulia Rahma14Adrian Joshua Velaro15Khairunnisa Khairunnnisa16Emil Salim17Fahrul Nurkolis18Rony Abdi Syahputra19Universitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraUniversitas Sumatera UtaraState Islamic University of Sunan Kalijaga (UIN Sunan Kalijaga)Universitas Sumatera UtaraMalaria remains a significant public health challenge in Indonesia, with varying prevalence across regions, particularly in eastern provinces like Papua and West Papua. This parasitic disease, transmitted by Plasmodium-infected Anopheles mosquitoes, continues to burden affected populations. Contemporary treatment approaches predominantly rely on Artemisinin-based Combination Therapy (ACT). However, the emergence of drug resistance, coupled with environmental and demographic factors, presents ongoing challenges. This paper explores current malaria treatment strategies in Indonesia, emphasizing the importance of vigilance in the face of drug resistance and the need for innovative approaches. Additionally, it discusses the potential of herbal interventions, drawing from the rich traditional knowledge of medicinal plants in Indonesia. Secondary metabolites found in herbs, including flavonoids, terpenoids, and alkaloids, show promise as antimalarial agents. As Indonesia and the global community strive to combat malaria, research, surveillance, and healthcare infrastructure development must remain at the forefront of strategies. Despite the complex nature of malaria control, continued dedication and collaboration offer hope for reducing the disease’s impact and progressing towards its eventual elimination. Graphical abstract:https://pharmacia.pensoft.net/article/116095/download/pdf/ |
| spellingShingle | Tina Christina L. Tobing Wahrianto Eka Saputri Nasywa Inayah Wafa Putri Daffa Zulfianti Lidwina Iswari Sihaloho Annisa Rabbiatul Husna Devia Salsabila Fito Hansen Hotasi Silalahi Alex Insandus Sitohang Aysiah Sabrina Atika Darayani Hasyati Harianja Silvyani Agustilova Barus Salwa Sabina Annisa Aulia Rahma Adrian Joshua Velaro Khairunnisa Khairunnnisa Emil Salim Fahrul Nurkolis Rony Abdi Syahputra Malaria in Indonesia: current treatment approaches, future strategies, and potential herbal interventions Pharmacia |
| title | Malaria in Indonesia: current treatment approaches, future strategies, and potential herbal interventions |
| title_full | Malaria in Indonesia: current treatment approaches, future strategies, and potential herbal interventions |
| title_fullStr | Malaria in Indonesia: current treatment approaches, future strategies, and potential herbal interventions |
| title_full_unstemmed | Malaria in Indonesia: current treatment approaches, future strategies, and potential herbal interventions |
| title_short | Malaria in Indonesia: current treatment approaches, future strategies, and potential herbal interventions |
| title_sort | malaria in indonesia current treatment approaches future strategies and potential herbal interventions |
| url | https://pharmacia.pensoft.net/article/116095/download/pdf/ |
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