A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation
Introduction: Psoriasis is a genetically determined chronic disease of skin in which a number of biochemical alterations take place during its course. The main objectives of our study were to calculate various biochemical parameters in psoriasis correlate them clinically. Materials and Methods:...
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Format: | Article |
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Our Dermatology Online
2014-04-01
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Online Access: | http://www.odermatol.com/issue-in-html/2014-2-6-study/ |
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author | Neerja Puri B B Mahajan |
author_facet | Neerja Puri B B Mahajan |
author_sort | Neerja Puri |
collection | DOAJ |
description | Introduction: Psoriasis is a genetically determined chronic disease of skin in which a number of biochemical alterations take place during its course. The main objectives of our study were to calculate various biochemical parameters in psoriasis correlate them clinically.
Materials and Methods: An attempt was made to detect the biochemical changes during its exacerbations. Fifty biopsy proved psoriasis patients were selected. Clinical examination and the various biochemical tests were performed at the time of enrollment and at the end of eight weeks of treatment.
Results: Hyperurecemia was seen in 16% patients and hypocalcemia was seen in 10 % patients and hypoalbuminaemia was seen in 56% patients.
Conclusion: With improvement of clinical picture, a shift of biochemical values towards normal was recorded. |
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format | Article |
id | doaj.art-421abb18e70547dabb0be9ba60de8ad9 |
institution | Directory Open Access Journal |
issn | 2081-9390 |
language | English |
last_indexed | 2024-04-12T23:34:52Z |
publishDate | 2014-04-01 |
publisher | Our Dermatology Online |
record_format | Article |
series | Nasza Dermatologia Online |
spelling | doaj.art-421abb18e70547dabb0be9ba60de8ad92022-12-22T03:12:11ZengOur Dermatology OnlineNasza Dermatologia Online2081-93902014-04-015213513910.7241/ourd.20142.32A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbationNeerja Puri0B B Mahajan1Department of Dermatology and Venereology, Punjab Health Systems Corporation, Ferozepur, Punjab, IndiaDepartment of Dermatology and Venereology, Punjab Health Systems Corporation, Ferozepur, Punjab, IndiaIntroduction: Psoriasis is a genetically determined chronic disease of skin in which a number of biochemical alterations take place during its course. The main objectives of our study were to calculate various biochemical parameters in psoriasis correlate them clinically. Materials and Methods: An attempt was made to detect the biochemical changes during its exacerbations. Fifty biopsy proved psoriasis patients were selected. Clinical examination and the various biochemical tests were performed at the time of enrollment and at the end of eight weeks of treatment. Results: Hyperurecemia was seen in 16% patients and hypocalcemia was seen in 10 % patients and hypoalbuminaemia was seen in 56% patients. Conclusion: With improvement of clinical picture, a shift of biochemical values towards normal was recorded.http://www.odermatol.com/issue-in-html/2014-2-6-study/PsoriasisbiochemicalPASI scorehypoalbuminaemiahyperuricaemiahypocalcaemia |
spellingShingle | Neerja Puri B B Mahajan A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation Nasza Dermatologia Online Psoriasis biochemical PASI score hypoalbuminaemia hyperuricaemia hypocalcaemia |
title | A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation |
title_full | A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation |
title_fullStr | A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation |
title_full_unstemmed | A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation |
title_short | A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation |
title_sort | study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation |
topic | Psoriasis biochemical PASI score hypoalbuminaemia hyperuricaemia hypocalcaemia |
url | http://www.odermatol.com/issue-in-html/2014-2-6-study/ |
work_keys_str_mv | AT neerjapuri astudyofclinicalandbiochemicalcorrelationinpatientsofpsoriasisinacuteexacerbation AT bbmahajan astudyofclinicalandbiochemicalcorrelationinpatientsofpsoriasisinacuteexacerbation AT neerjapuri studyofclinicalandbiochemicalcorrelationinpatientsofpsoriasisinacuteexacerbation AT bbmahajan studyofclinicalandbiochemicalcorrelationinpatientsofpsoriasisinacuteexacerbation |