A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation

Introduction: Psoriasis is a genetically determined chronic disease of skin in which a number of biochemical alterations take place during its course. The main objectives of our study were to calculate various biochemical parameters in psoriasis correlate them clinically. Materials and Methods:...

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Main Authors: Neerja Puri, B B Mahajan
Format: Article
Language:English
Published: Our Dermatology Online 2014-04-01
Series:Nasza Dermatologia Online
Subjects:
Online Access:http://www.odermatol.com/issue-in-html/2014-2-6-study/
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author Neerja Puri
B B Mahajan
author_facet Neerja Puri
B B Mahajan
author_sort Neerja Puri
collection DOAJ
description Introduction: Psoriasis is a genetically determined chronic disease of skin in which a number of biochemical alterations take place during its course. The main objectives of our study were to calculate various biochemical parameters in psoriasis correlate them clinically. Materials and Methods: An attempt was made to detect the biochemical changes during its exacerbations. Fifty biopsy proved psoriasis patients were selected. Clinical examination and the various biochemical tests were performed at the time of enrollment and at the end of eight weeks of treatment. Results: Hyperurecemia was seen in 16% patients and hypocalcemia was seen in 10 % patients and hypoalbuminaemia was seen in 56% patients. Conclusion: With improvement of clinical picture, a shift of biochemical values towards normal was recorded.
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spelling doaj.art-421abb18e70547dabb0be9ba60de8ad92022-12-22T03:12:11ZengOur Dermatology OnlineNasza Dermatologia Online2081-93902014-04-015213513910.7241/ourd.20142.32A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbationNeerja Puri0B B Mahajan1Department of Dermatology and Venereology, Punjab Health Systems Corporation, Ferozepur, Punjab, IndiaDepartment of Dermatology and Venereology, Punjab Health Systems Corporation, Ferozepur, Punjab, IndiaIntroduction: Psoriasis is a genetically determined chronic disease of skin in which a number of biochemical alterations take place during its course. The main objectives of our study were to calculate various biochemical parameters in psoriasis correlate them clinically. Materials and Methods: An attempt was made to detect the biochemical changes during its exacerbations. Fifty biopsy proved psoriasis patients were selected. Clinical examination and the various biochemical tests were performed at the time of enrollment and at the end of eight weeks of treatment. Results: Hyperurecemia was seen in 16% patients and hypocalcemia was seen in 10 % patients and hypoalbuminaemia was seen in 56% patients. Conclusion: With improvement of clinical picture, a shift of biochemical values towards normal was recorded.http://www.odermatol.com/issue-in-html/2014-2-6-study/PsoriasisbiochemicalPASI scorehypoalbuminaemiahyperuricaemiahypocalcaemia
spellingShingle Neerja Puri
B B Mahajan
A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation
Nasza Dermatologia Online
Psoriasis
biochemical
PASI score
hypoalbuminaemia
hyperuricaemia
hypocalcaemia
title A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation
title_full A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation
title_fullStr A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation
title_full_unstemmed A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation
title_short A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation
title_sort study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation
topic Psoriasis
biochemical
PASI score
hypoalbuminaemia
hyperuricaemia
hypocalcaemia
url http://www.odermatol.com/issue-in-html/2014-2-6-study/
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