STUDY OF FUNGAL INFECTION IN PATIENTS WITH LEUKAEMIA

Fungal infections most commonly occur as complications in immunocompromised patients especially in patients with haematologic malignancies. Fifty two leukaemic patients (29 All, 22 AML, 1CML) examined for fungal infections. The majority of those patients had fever of undetermined origin, profound le...

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Main Authors: F Zaini, Sh Basiri Djahromi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 1994-06-01
Series:Iranian Journal of Public Health
Online Access:https://ijph.tums.ac.ir/index.php/ijph/article/view/1575
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author F Zaini
Sh Basiri Djahromi
author_facet F Zaini
Sh Basiri Djahromi
author_sort F Zaini
collection DOAJ
description Fungal infections most commonly occur as complications in immunocompromised patients especially in patients with haematologic malignancies. Fifty two leukaemic patients (29 All, 22 AML, 1CML) examined for fungal infections. The majority of those patients had fever of undetermined origin, profound leucopenia and had been under treatment of cytotoxics, corticosteroids and antibiotics for prolonged period of time. The study group consisted of 29 males and 23 females and ranged in age from 4 months to 55 years. Diagnosis was established by demonstration of fungus in direct and cultural examinations. In the present study one case of pulmonary aspergillosis due to Aspergillus flavus associated with candidiasis due to Candida albicans, one case of pulmonary mucoromycosis due to Mucor sp. Associated with candidaenia due to C.tropicalis, one case of pulmonary geotrichosis due to Geotrichum candidum, one case fungaemia due to Rhodotorula rubra associated with an undetermined black yeast, two cases of pulmonary candidiasis due to C.albicans and C.tropicalis were observed. C.albicans was the most frequent fungal invader in this study and pulmonary mucoromycosis and geotrichosis are reported for the first time from Iran.
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spelling doaj.art-422039d9d7754a099d753f339aa97d4c2022-12-21T23:12:50ZengTehran University of Medical SciencesIranian Journal of Public Health2251-60852251-60931994-06-01231-41564STUDY OF FUNGAL INFECTION IN PATIENTS WITH LEUKAEMIA F Zaini0 Sh Basiri Djahromi1 Fungal infections most commonly occur as complications in immunocompromised patients especially in patients with haematologic malignancies. Fifty two leukaemic patients (29 All, 22 AML, 1CML) examined for fungal infections. The majority of those patients had fever of undetermined origin, profound leucopenia and had been under treatment of cytotoxics, corticosteroids and antibiotics for prolonged period of time. The study group consisted of 29 males and 23 females and ranged in age from 4 months to 55 years. Diagnosis was established by demonstration of fungus in direct and cultural examinations. In the present study one case of pulmonary aspergillosis due to Aspergillus flavus associated with candidiasis due to Candida albicans, one case of pulmonary mucoromycosis due to Mucor sp. Associated with candidaenia due to C.tropicalis, one case of pulmonary geotrichosis due to Geotrichum candidum, one case fungaemia due to Rhodotorula rubra associated with an undetermined black yeast, two cases of pulmonary candidiasis due to C.albicans and C.tropicalis were observed. C.albicans was the most frequent fungal invader in this study and pulmonary mucoromycosis and geotrichosis are reported for the first time from Iran.https://ijph.tums.ac.ir/index.php/ijph/article/view/1575
spellingShingle F Zaini
Sh Basiri Djahromi
STUDY OF FUNGAL INFECTION IN PATIENTS WITH LEUKAEMIA
Iranian Journal of Public Health
title STUDY OF FUNGAL INFECTION IN PATIENTS WITH LEUKAEMIA
title_full STUDY OF FUNGAL INFECTION IN PATIENTS WITH LEUKAEMIA
title_fullStr STUDY OF FUNGAL INFECTION IN PATIENTS WITH LEUKAEMIA
title_full_unstemmed STUDY OF FUNGAL INFECTION IN PATIENTS WITH LEUKAEMIA
title_short STUDY OF FUNGAL INFECTION IN PATIENTS WITH LEUKAEMIA
title_sort study of fungal infection in patients with leukaemia
url https://ijph.tums.ac.ir/index.php/ijph/article/view/1575
work_keys_str_mv AT fzaini studyoffungalinfectioninpatientswithleukaemia
AT shbasiridjahromi studyoffungalinfectioninpatientswithleukaemia