High resolution crystal structures of the receptor-binding domain of Clostridium botulinum neurotoxin serotypes A and FA
The binding specificity of botulinum neurotoxins (BoNTs) is primarily a consequence of their ability to bind to multiple receptors at the same time. BoNTs consist of three distinct domains, a metalloprotease light chain (LC), a translocation domain (HN) and a receptor-binding domain (HC). Here we re...
Main Authors: | Jonathan R. Davies, Gavin S. Hackett, Sai Man Liu, K. Ravi Acharya |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2018-03-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/4552.pdf |
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