Change of Apparent Diffusion Coefficient Immediately after Recanalization through Intra-Arterial Revascularization Therapy in Acute Ischemic Stroke
Purpose Intra-arterial revascularization therapy (IART) for acute ischemic stroke has become increasingly popular recently. However, early change in apparent diffusion coefficient (ADC) values after full recanalization in human stroke has not received much attention. The aim of this study was to ev...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
The Korean Society of Radiology
2016-04-01
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| Series: | 대한영상의학회지 |
| Subjects: | |
| Online Access: | https://doi.org/10.3348/jksr.2016.74.4.245 |
| _version_ | 1818327988355203072 |
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| author | Jieun Roh Jeong A Yeom Young Soo Kim Chang Hyo Yoon Min-Gyu Park Kyung-Pil Park Seung Kug Baik |
| author_facet | Jieun Roh Jeong A Yeom Young Soo Kim Chang Hyo Yoon Min-Gyu Park Kyung-Pil Park Seung Kug Baik |
| author_sort | Jieun Roh |
| collection | DOAJ |
| description | Purpose
Intra-arterial revascularization therapy (IART) for acute ischemic stroke has become increasingly popular recently. However, early change in apparent diffusion coefficient (ADC) values after full recanalization in human stroke has not received much attention. The aim of this study was to evaluate ADC changes immediately after interventional full-recanalization in patients with acute ischemic stroke.
Materials and Methods
ADC values of 25 lesions from 18 acute ischemic stroke patients were recorded with both pre- and post-recanalization ADC maps. Measurement was done by placing region of interests over the representative images of the lesion. For analysis, lesions were divided into territorial infarction (TI) and watershed infarction (WI).
Results
Mean ADC values of the overall 25 lesions before IART were 415.12 × 10-6 mm2/sec, and increased to 619.08 × 10-6 mm2/sec after the IART. Average relative ADC (rADC) value for 22 TI increased from 0.59 to 0.92 (p < 0.000), whereas, average rADC value for 3 WI did not change significantly.
Conclusion
There was a conspicuous increase of ADC values immediately after full-recanalization in TI lesions. On the other hand, WI lesions did not show significant change in ADC values after recanalization. |
| first_indexed | 2024-12-13T12:25:01Z |
| format | Article |
| id | doaj.art-422780cd067d47409123000f2a0738ec |
| institution | Directory Open Access Journal |
| issn | 1738-2637 2288-2928 |
| language | English |
| last_indexed | 2024-12-13T12:25:01Z |
| publishDate | 2016-04-01 |
| publisher | The Korean Society of Radiology |
| record_format | Article |
| series | 대한영상의학회지 |
| spelling | doaj.art-422780cd067d47409123000f2a0738ec2022-12-21T23:46:23ZengThe Korean Society of Radiology대한영상의학회지1738-26372288-29282016-04-01744245253https://doi.org/10.3348/jksr.2016.74.4.245Change of Apparent Diffusion Coefficient Immediately after Recanalization through Intra-Arterial Revascularization Therapy in Acute Ischemic StrokeJieun Roh0Jeong A Yeom1Young Soo Kim2Chang Hyo Yoon3Min-Gyu Park4Kyung-Pil Park5Seung Kug Baik6Department of Radiology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Radiology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Neurosurgery, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Radiology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Neurology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Neurology, Pusan National University Yangsan Hospital, Yangsan, KoreaDepartment of Radiology, Pusan National University Yangsan Hospital, Yangsan, KoreaPurpose Intra-arterial revascularization therapy (IART) for acute ischemic stroke has become increasingly popular recently. However, early change in apparent diffusion coefficient (ADC) values after full recanalization in human stroke has not received much attention. The aim of this study was to evaluate ADC changes immediately after interventional full-recanalization in patients with acute ischemic stroke. Materials and Methods ADC values of 25 lesions from 18 acute ischemic stroke patients were recorded with both pre- and post-recanalization ADC maps. Measurement was done by placing region of interests over the representative images of the lesion. For analysis, lesions were divided into territorial infarction (TI) and watershed infarction (WI). Results Mean ADC values of the overall 25 lesions before IART were 415.12 × 10-6 mm2/sec, and increased to 619.08 × 10-6 mm2/sec after the IART. Average relative ADC (rADC) value for 22 TI increased from 0.59 to 0.92 (p < 0.000), whereas, average rADC value for 3 WI did not change significantly. Conclusion There was a conspicuous increase of ADC values immediately after full-recanalization in TI lesions. On the other hand, WI lesions did not show significant change in ADC values after recanalization.https://doi.org/10.3348/jksr.2016.74.4.245magnetic resonance imagingmechanical thrombolysisstrokecerebral infarctionreperfusion |
| spellingShingle | Jieun Roh Jeong A Yeom Young Soo Kim Chang Hyo Yoon Min-Gyu Park Kyung-Pil Park Seung Kug Baik Change of Apparent Diffusion Coefficient Immediately after Recanalization through Intra-Arterial Revascularization Therapy in Acute Ischemic Stroke 대한영상의학회지 magnetic resonance imaging mechanical thrombolysis stroke cerebral infarction reperfusion |
| title | Change of Apparent Diffusion Coefficient Immediately after Recanalization through Intra-Arterial Revascularization Therapy in Acute Ischemic Stroke |
| title_full | Change of Apparent Diffusion Coefficient Immediately after Recanalization through Intra-Arterial Revascularization Therapy in Acute Ischemic Stroke |
| title_fullStr | Change of Apparent Diffusion Coefficient Immediately after Recanalization through Intra-Arterial Revascularization Therapy in Acute Ischemic Stroke |
| title_full_unstemmed | Change of Apparent Diffusion Coefficient Immediately after Recanalization through Intra-Arterial Revascularization Therapy in Acute Ischemic Stroke |
| title_short | Change of Apparent Diffusion Coefficient Immediately after Recanalization through Intra-Arterial Revascularization Therapy in Acute Ischemic Stroke |
| title_sort | change of apparent diffusion coefficient immediately after recanalization through intra arterial revascularization therapy in acute ischemic stroke |
| topic | magnetic resonance imaging mechanical thrombolysis stroke cerebral infarction reperfusion |
| url | https://doi.org/10.3348/jksr.2016.74.4.245 |
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