A Case of Concurrent Extramammary Paget Disease and Basal Cell Carcinoma of the Perianal Region
Summary:. An 83-year-old Japanese man who had been aware of a tumor near his anus for 2 years underwent tumor resection. Although he was diagnosed with basal cell carcinoma (BCC), extramammary Paget disease (EMPD) was also accidentally found in the same specimen. In the pathological histology of EMP...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer
2020-01-01
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| Series: | Plastic and Reconstructive Surgery, Global Open |
| Online Access: | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002602 |
| _version_ | 1818555905400111104 |
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| author | Natsuko Takahashi, MD Yoshiyuki Okumura, MD Eiichi Sawaragi, MD |
| author_facet | Natsuko Takahashi, MD Yoshiyuki Okumura, MD Eiichi Sawaragi, MD |
| author_sort | Natsuko Takahashi, MD |
| collection | DOAJ |
| description | Summary:. An 83-year-old Japanese man who had been aware of a tumor near his anus for 2 years underwent tumor resection. Although he was diagnosed with basal cell carcinoma (BCC), extramammary Paget disease (EMPD) was also accidentally found in the same specimen. In the pathological histology of EMPD, there were large round cells with ample cytoplasm spread in the epidermis; these cells were positive for cytokeratin 7 and gross cystic disease fluid protein 15. No signs that are typically associated with EMPD, such as erythema or leukoderma, were observed near the anus. There have been only 4 reports in which BCC and EMPD developed in the same area, and the authors present the fifth case. In the reported case, no clear evidence was found for the corelative development of BCC and EMPD. |
| first_indexed | 2024-12-13T02:59:05Z |
| format | Article |
| id | doaj.art-4227baa0385c4fae90a61496d40ae908 |
| institution | Directory Open Access Journal |
| issn | 2169-7574 |
| language | English |
| last_indexed | 2024-12-13T02:59:05Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Plastic and Reconstructive Surgery, Global Open |
| spelling | doaj.art-4227baa0385c4fae90a61496d40ae9082022-12-22T00:01:52ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742020-01-0181e260210.1097/GOX.0000000000002602202001000-00036A Case of Concurrent Extramammary Paget Disease and Basal Cell Carcinoma of the Perianal RegionNatsuko Takahashi, MD0Yoshiyuki Okumura, MD1Eiichi Sawaragi, MD2From the Department of Plastic and Reconstructive Surgery, Japanese Red Cross Society Wakayama Medical Center, Wakayama-Shi, Wakayama, Japan.From the Department of Plastic and Reconstructive Surgery, Japanese Red Cross Society Wakayama Medical Center, Wakayama-Shi, Wakayama, Japan.From the Department of Plastic and Reconstructive Surgery, Japanese Red Cross Society Wakayama Medical Center, Wakayama-Shi, Wakayama, Japan.Summary:. An 83-year-old Japanese man who had been aware of a tumor near his anus for 2 years underwent tumor resection. Although he was diagnosed with basal cell carcinoma (BCC), extramammary Paget disease (EMPD) was also accidentally found in the same specimen. In the pathological histology of EMPD, there were large round cells with ample cytoplasm spread in the epidermis; these cells were positive for cytokeratin 7 and gross cystic disease fluid protein 15. No signs that are typically associated with EMPD, such as erythema or leukoderma, were observed near the anus. There have been only 4 reports in which BCC and EMPD developed in the same area, and the authors present the fifth case. In the reported case, no clear evidence was found for the corelative development of BCC and EMPD.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002602 |
| spellingShingle | Natsuko Takahashi, MD Yoshiyuki Okumura, MD Eiichi Sawaragi, MD A Case of Concurrent Extramammary Paget Disease and Basal Cell Carcinoma of the Perianal Region Plastic and Reconstructive Surgery, Global Open |
| title | A Case of Concurrent Extramammary Paget Disease and Basal Cell Carcinoma of the Perianal Region |
| title_full | A Case of Concurrent Extramammary Paget Disease and Basal Cell Carcinoma of the Perianal Region |
| title_fullStr | A Case of Concurrent Extramammary Paget Disease and Basal Cell Carcinoma of the Perianal Region |
| title_full_unstemmed | A Case of Concurrent Extramammary Paget Disease and Basal Cell Carcinoma of the Perianal Region |
| title_short | A Case of Concurrent Extramammary Paget Disease and Basal Cell Carcinoma of the Perianal Region |
| title_sort | case of concurrent extramammary paget disease and basal cell carcinoma of the perianal region |
| url | http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000002602 |
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