| Summary: | Objective: To study the content of serum inflammatory medium of the patients
complicated with acute intestinal obstruction after the surgery of colon cancer.
Methods: A total of 150 patients with colon cancer received limited surgery treatment
during the period of May 2012 to October 2015 were selected as the study objects. They
were divided into postoperative ileus (POI) group and non-postoperative ileus (non-POI)
group according to the presence or absence of intestinal obstruction. Then, the contents of
serum procalcitonin (PCT), C-reactive protein (CRP), tumor necrosis factor-alpha (TNFa) and interleukin-6 (IL-6) were detected at the 1st, 3rd, 5th and 7th days after the
surgery.
Results: The levels of serum PCT, CRP, TNF-a and IL-6 of two groups at the 1st day
had no differences after the surgery. The level of serum PCT of POI group tended to
increase and its levels of serum CRP, TNF-a and IL-6 tended to decrease at the 3rd, 5th
and 7th days after the surgery, while the levels of serum PCT, CRP, TNF-a and IL-6 of
non-POI group were decreased. The content of serum PCT of POI group and non-POI
group at the 3rd day after the surgery had no differences (P > 0.05), and the level of
serum PCT of POI group was higher than that of non-POI group at the 5th and 7th days
after the surgery (P < 0.05). The levels of serum CRP, TNF-a and IL-6 of POI group and
non-POI group had no differences at the 3rd, 5th and 7th days after the surgery
(P > 0.05).
Conclusions: The raising of the content of serum PCT after the surgery can be used as
the laboratory index to predict the incidence of acute intestinal obstruction after the
surgery of colon cancer.
1. Introduction
Postoperative ileus (POI) mainly happens after major
abdominal surgeries causing the clinical symptoms such as
abdominal pain, abdominal distension, no flatus and defecation,
etc. Colorectal cancer is a common malignant tumor in the
digestive system, and the incidence and death rates of the disease
were all tending to in
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