Proteomics of protein trafficking by in vivo tissue-specific labeling

Proteomics of protein trafficking by in vivo tissue-specific labeling

The network of proteins secreted for interorgan communication is poorly understood. Here, the authors develop a method, based on protein labeling, to study cell-specific secretomes and interorgan protein trafficking, and demonstrate their approach in Drosophila and mouse models.

Bibliographic Details
Main Authors: Ilia A. Droujinine, Amanda S. Meyer, Dan Wang, Namrata D. Udeshi, Yanhui Hu, David Rocco, Jill A. McMahon, Rui Yang, JinJin Guo, Luye Mu, Dominique K. Carey, Tanya Svinkina, Rebecca Zeng, Tess Branon, Areya Tabatabai, Justin A. Bosch, John M. Asara, Alice Y. Ting, Steven A. Carr, Andrew P. McMahon, Norbert Perrimon
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22599-x

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