LPS nephropathy in mice is ameliorated by IL-2 independently of regulatory T cells activity.

LPS nephropathy in mice is ameliorated by IL-2 independently of regulatory T cells activity.

Immunosuppressive regulatory T cells (Tregs) have been hypothesized to exert a protective role in animal models of spontaneous (Buffalo/Mna) and/or drug induced (Adriamycin) nephrotic syndrome. In this study, we thought to define whether Tregs can modify the outcome of LPS nephropathy utilizing IL-2...

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Bibliographic Details
Main Authors: Roberta Bertelli, Armando Di Donato, Michela Cioni, Fabio Grassi, Masami Ikehata, Alice Bonanni, Maria Pia Rastaldi, Gian Marco Ghiggeri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4208845?pdf=render

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