Thrombolysis in the de winter electrocardiography pattern: A therapeutic dilemma

The de Winter's pattern is an electrocardiography (ECG) finding characterized by ST depression and tall prominent T-waves in precordial leads with ST elevation in lead aVR. It signifies the occlusion of proximal left anterior descending artery (LAD). Although it is considered a ST-elevation myo...

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Main Authors: Amit Kumar, Rajesh Chetiwal, Shweta Tanwar, Sudhish Gupta, Rohit Kumar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Journal of the Practice of Cardiovascular Sciences
Subjects:
Online Access:http://www.j-pcs.org/article.asp?issn=2395-5414;year=2022;volume=8;issue=1;spage=48;epage=50;aulast=Kumar
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author Amit Kumar
Rajesh Chetiwal
Shweta Tanwar
Sudhish Gupta
Rohit Kumar
author_facet Amit Kumar
Rajesh Chetiwal
Shweta Tanwar
Sudhish Gupta
Rohit Kumar
author_sort Amit Kumar
collection DOAJ
description The de Winter's pattern is an electrocardiography (ECG) finding characterized by ST depression and tall prominent T-waves in precordial leads with ST elevation in lead aVR. It signifies the occlusion of proximal left anterior descending artery (LAD). Although it is considered a ST-elevation myocardial infarction (STEMI) equivalent, current guidelines recommend against the use of thrombolytic therapy in the absence of STEMI. As the question whether to use thrombolysis in such situations remains unanswered and controversial, we preferred to provide thrombolytic therapy with tenecteplase to our patient admitted with acute retrosternal chest pain with de Winter's ECG pattern so as to prevent myocardial damage and improve the patient outcome as the percutaneous coronary intervention facility was not immediately available. The thrombolysis was successful and the proximal LAD occlusion was confirmed later on coronary angiography which was treated with stent implantation. This case report tends to highlight the therapeutic dilemma while managing patients with de Winter's ECG pattern.
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spelling doaj.art-423141cf3cf34553bf76963c6ec7d8052022-12-22T00:25:31ZengWolters Kluwer Medknow PublicationsJournal of the Practice of Cardiovascular Sciences2395-54142454-28302022-01-0181485010.4103/jpcs.jpcs_4_22Thrombolysis in the de winter electrocardiography pattern: A therapeutic dilemmaAmit KumarRajesh ChetiwalShweta TanwarSudhish GuptaRohit KumarThe de Winter's pattern is an electrocardiography (ECG) finding characterized by ST depression and tall prominent T-waves in precordial leads with ST elevation in lead aVR. It signifies the occlusion of proximal left anterior descending artery (LAD). Although it is considered a ST-elevation myocardial infarction (STEMI) equivalent, current guidelines recommend against the use of thrombolytic therapy in the absence of STEMI. As the question whether to use thrombolysis in such situations remains unanswered and controversial, we preferred to provide thrombolytic therapy with tenecteplase to our patient admitted with acute retrosternal chest pain with de Winter's ECG pattern so as to prevent myocardial damage and improve the patient outcome as the percutaneous coronary intervention facility was not immediately available. The thrombolysis was successful and the proximal LAD occlusion was confirmed later on coronary angiography which was treated with stent implantation. This case report tends to highlight the therapeutic dilemma while managing patients with de Winter's ECG pattern.http://www.j-pcs.org/article.asp?issn=2395-5414;year=2022;volume=8;issue=1;spage=48;epage=50;aulast=Kumarde winter's patternelectrocardiographystemi equivalentsthrombolysis
spellingShingle Amit Kumar
Rajesh Chetiwal
Shweta Tanwar
Sudhish Gupta
Rohit Kumar
Thrombolysis in the de winter electrocardiography pattern: A therapeutic dilemma
Journal of the Practice of Cardiovascular Sciences
de winter's pattern
electrocardiography
stemi equivalents
thrombolysis
title Thrombolysis in the de winter electrocardiography pattern: A therapeutic dilemma
title_full Thrombolysis in the de winter electrocardiography pattern: A therapeutic dilemma
title_fullStr Thrombolysis in the de winter electrocardiography pattern: A therapeutic dilemma
title_full_unstemmed Thrombolysis in the de winter electrocardiography pattern: A therapeutic dilemma
title_short Thrombolysis in the de winter electrocardiography pattern: A therapeutic dilemma
title_sort thrombolysis in the de winter electrocardiography pattern a therapeutic dilemma
topic de winter's pattern
electrocardiography
stemi equivalents
thrombolysis
url http://www.j-pcs.org/article.asp?issn=2395-5414;year=2022;volume=8;issue=1;spage=48;epage=50;aulast=Kumar
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AT rajeshchetiwal thrombolysisinthedewinterelectrocardiographypatternatherapeuticdilemma
AT shwetatanwar thrombolysisinthedewinterelectrocardiographypatternatherapeuticdilemma
AT sudhishgupta thrombolysisinthedewinterelectrocardiographypatternatherapeuticdilemma
AT rohitkumar thrombolysisinthedewinterelectrocardiographypatternatherapeuticdilemma