Excitatory and feed-forward inhibitory hippocampal synapses work synergistically as an adaptive filter of natural spike trains.

Short-term synaptic plasticity (STP) is an important mechanism for modifying neural circuits during computation. Although STP is much studied, its role in the processing of complex natural spike patterns is unknown. Here we analyze the responses of excitatory and inhibitory hippocampal synapses to n...

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Bibliographic Details
Main Authors: Vitaly A Klyachko, Charles F Stevens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-07-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1479695?pdf=render

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