Comparion of two techniques crosslinking for progressive keratectasia

<p><strong>Purpose</strong>: to compare surgical approaches, features of the postoperative period and functional results of conventional and opti- mized crosslinking techniques.<br /><strong>Methods</strong>: We followed 2 groups of patients (10 patients, 10 eyes...

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Main Authors: L. N. Boriskina, I. A. Remesnikov, E. S. Blinkova, E. G. Solodkova
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2014-07-01
Series:Oftalʹmologiâ
Subjects:
Online Access:http://www.ophthalmojournal.com/index.php/opht/article/view/131
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author L. N. Boriskina
I. A. Remesnikov
E. S. Blinkova
E. G. Solodkova
author_facet L. N. Boriskina
I. A. Remesnikov
E. S. Blinkova
E. G. Solodkova
author_sort L. N. Boriskina
collection DOAJ
description <p><strong>Purpose</strong>: to compare surgical approaches, features of the postoperative period and functional results of conventional and opti- mized crosslinking techniques.<br /><strong>Methods</strong>: We followed 2 groups of patients (10 patients, 10 eyes each), treated in Volgograd branch of the S.N. Fyodorov Eye Microsurgery Clinic for kerotoconus of the II-III degree according to the conventional method (I group) and the optimized technique (II group). the optimized technique consisted of the customized excimer laser corneal deepitalization to the depth of 2/3 of the epithelial layer. Excimer laser ablation with intraoperative «on-line» pachymetry was made by means of Schwind Amaris-500 Hz (Schwind, Germany).<br /><strong>Results</strong>: Method of the optimized crosslinking with a customized depth of excimer laser ablation required a longer period for satu- ration of the cornea with solution of riboflavin (mean 5-10 minutes). However, it was accompanied with a less severe corneal syndrome, a complete reepithelization and an earlier postoperative recovery of visual functions. Six months postoperatively a 1-2-line improve- ment of BCVA and UCVA was achieved in 19 patients (19 eyes). Decrease of cylindrical component averaged 1.2 D in the group I and 1 D in the group II. Mean refraction change in SE was 2.2 D in the group I and 2.0 D in the group II. Six months postoperatively one patient from the group II had a 1-line regression of BCVA in comparison to the preoperative level accompanied with a 10 μm corneal thinning and corneal curvature steepening by 2 D at the top of keratoconus, which was regarded as an aggravation of initial state.<br /><strong>Conclusion</strong>: Both approaches have proved their safety and effectiveness. However, incurrence of the above-mentioned case of state deterioration calls for the further comparative studies in order to evaluate clinical effectiveness of these methods.</p>
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spelling doaj.art-423df322025940d6be4a138ff991de612022-12-22T01:39:20ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952014-07-01921821131Comparion of two techniques crosslinking for progressive keratectasiaL. N. Boriskina0I. A. Remesnikov1E. S. Blinkova2E. G. Solodkova3Волгоградский филиал ФГУ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова Росмедтехнологии», Волгоград, РоссияВолгоградский филиал ФГУ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова Росмедтехнологии», Волгоград, РоссияВолгоградский филиал ФГУ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова Росмедтехнологии», Волгоград, РоссияВолгоградский филиал ФГУ «МНТК «Микрохирургия глаза» им. акад. С.Н. Федорова Росмедтехнологии», Волгоград, Россия<p><strong>Purpose</strong>: to compare surgical approaches, features of the postoperative period and functional results of conventional and opti- mized crosslinking techniques.<br /><strong>Methods</strong>: We followed 2 groups of patients (10 patients, 10 eyes each), treated in Volgograd branch of the S.N. Fyodorov Eye Microsurgery Clinic for kerotoconus of the II-III degree according to the conventional method (I group) and the optimized technique (II group). the optimized technique consisted of the customized excimer laser corneal deepitalization to the depth of 2/3 of the epithelial layer. Excimer laser ablation with intraoperative «on-line» pachymetry was made by means of Schwind Amaris-500 Hz (Schwind, Germany).<br /><strong>Results</strong>: Method of the optimized crosslinking with a customized depth of excimer laser ablation required a longer period for satu- ration of the cornea with solution of riboflavin (mean 5-10 minutes). However, it was accompanied with a less severe corneal syndrome, a complete reepithelization and an earlier postoperative recovery of visual functions. Six months postoperatively a 1-2-line improve- ment of BCVA and UCVA was achieved in 19 patients (19 eyes). Decrease of cylindrical component averaged 1.2 D in the group I and 1 D in the group II. Mean refraction change in SE was 2.2 D in the group I and 2.0 D in the group II. Six months postoperatively one patient from the group II had a 1-line regression of BCVA in comparison to the preoperative level accompanied with a 10 μm corneal thinning and corneal curvature steepening by 2 D at the top of keratoconus, which was regarded as an aggravation of initial state.<br /><strong>Conclusion</strong>: Both approaches have proved their safety and effectiveness. However, incurrence of the above-mentioned case of state deterioration calls for the further comparative studies in order to evaluate clinical effectiveness of these methods.</p>http://www.ophthalmojournal.com/index.php/opht/article/view/131progressive keratectasiacrosslinkingcorneal collagen
spellingShingle L. N. Boriskina
I. A. Remesnikov
E. S. Blinkova
E. G. Solodkova
Comparion of two techniques crosslinking for progressive keratectasia
Oftalʹmologiâ
progressive keratectasia
crosslinking
corneal collagen
title Comparion of two techniques crosslinking for progressive keratectasia
title_full Comparion of two techniques crosslinking for progressive keratectasia
title_fullStr Comparion of two techniques crosslinking for progressive keratectasia
title_full_unstemmed Comparion of two techniques crosslinking for progressive keratectasia
title_short Comparion of two techniques crosslinking for progressive keratectasia
title_sort comparion of two techniques crosslinking for progressive keratectasia
topic progressive keratectasia
crosslinking
corneal collagen
url http://www.ophthalmojournal.com/index.php/opht/article/view/131
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AT esblinkova comparionoftwotechniquescrosslinkingforprogressivekeratectasia
AT egsolodkova comparionoftwotechniquescrosslinkingforprogressivekeratectasia