Chromatin Imbalance as the Vertex Between Fetal Valproate Syndrome and Chromatinopathies

Chromatin Imbalance as the Vertex Between Fetal Valproate Syndrome and Chromatinopathies

Prenatal exposure to valproate (VPA), an antiepileptic drug, has been associated with fetal valproate spectrum disorders (FVSD), a clinical condition including congenital malformations, developmental delay, intellectual disability as well as autism spectrum disorder, together with a distinctive faci...

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Bibliographic Details
Main Authors: Chiara Parodi, Elisabetta Di Fede, Angela Peron, Ilaria Viganò, Paolo Grazioli, Silvia Castiglioni, Richard H. Finnell, Cristina Gervasini, Aglaia Vignoli, Valentina Massa
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
fetal valproate syndrome
chromatinopathies
anti-epileptic drugs
neurodevelopment
HDAC inhibitor
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.654467/full

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