The association between inflammatory markers and obesity-related factors in Tehranian adults: Tehran lipid and glucose study
Objective(s):Obesity considered being a low-grade inflammatory disease. The objective of this study was to examine the association between inflammatory markers (IM) including C-reactive protein (hs-CRP), Interleukin-6 (IL-6), and homocystein (Hcy) and obesity[F1] -related factors (e.g. BMI, waist, h...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2014-08-01
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| Series: | Iranian Journal of Basic Medical Sciences |
| Subjects: | |
| Online Access: | http://ijbms.mums.ac.ir/pdf_3189_7576c6383629cf3af4d6666eb3f2f81e.html |
| _version_ | 1828740148674691072 |
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| author | Bita Faam Maryam Zarkesh Maryam Sadat Daneshpour Fereidoun Azizi Mehdi Hedayati |
| author_facet | Bita Faam Maryam Zarkesh Maryam Sadat Daneshpour Fereidoun Azizi Mehdi Hedayati |
| author_sort | Bita Faam |
| collection | DOAJ |
| description | Objective(s):Obesity considered being a low-grade inflammatory disease. The objective of this study was to examine the association between inflammatory markers (IM) including C-reactive protein (hs-CRP), Interleukin-6 (IL-6), and homocystein (Hcy) and obesity[F1] -related factors (e.g. BMI, waist, hip) in adult participants of Tehran lipid and glucose study (TLGS).
Materials and Methods: In this cross-sectional study, 352 individuals (132 men and 220 women), age ≥19 years, were randomly recruited from participants of TLGS population[F2] . The serum levels of hs-CRP, IL-6, Hcy were determined using the enzyme linked immunosorbent assay (ELISA) method[F3] . Variables were compared by sample t-test. Bivariate linear correlation was estimated using Pearson’s correlation coefficient. Linear regression analysis was applied to investigate the association between IMs and anthropometric and biochemical variables.
Results: The mean age of participants was 46.1±16.1 years. abdominal obesity was present in 199(56.5%) individuals. levels of hs-CRP and IL-6 increased in the abdominally obese group (1507±3.3 vs. 577.8±4.3 ng/ml P |
| first_indexed | 2024-04-13T00:35:24Z |
| format | Article |
| id | doaj.art-4248b2da82b5454ab1e23fa430efae0a |
| institution | Directory Open Access Journal |
| issn | 2008-3866 2008-3874 |
| language | English |
| last_indexed | 2024-04-13T00:35:24Z |
| publishDate | 2014-08-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Basic Medical Sciences |
| spelling | doaj.art-4248b2da82b5454ab1e23fa430efae0a2022-12-22T03:10:20ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences2008-38662008-38742014-08-011785775823189The association between inflammatory markers and obesity-related factors in Tehranian adults: Tehran lipid and glucose studyBita Faam0Maryam Zarkesh1Maryam Sadat Daneshpour2Fereidoun Azizi3Mehdi Hedayati41 Cellular and Molecular Research Center, Obesity Research Center, Research Institute for Endocrine Sciences Shahid Beheshti University of Medical Sciences, Tehran, Iran1 Cellular and Molecular Research Center, Obesity Research Center, Research Institute for Endocrine Sciences Shahid Beheshti University of Medical Sciences, Tehran, Iran1 Cellular and Molecular Research Center, Obesity Research Center, Research Institute for Endocrine Sciences Shahid Beheshti University of Medical Sciences, Tehran, IranEndocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IranEndocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IranObjective(s):Obesity considered being a low-grade inflammatory disease. The objective of this study was to examine the association between inflammatory markers (IM) including C-reactive protein (hs-CRP), Interleukin-6 (IL-6), and homocystein (Hcy) and obesity[F1] -related factors (e.g. BMI, waist, hip) in adult participants of Tehran lipid and glucose study (TLGS). Materials and Methods: In this cross-sectional study, 352 individuals (132 men and 220 women), age ≥19 years, were randomly recruited from participants of TLGS population[F2] . The serum levels of hs-CRP, IL-6, Hcy were determined using the enzyme linked immunosorbent assay (ELISA) method[F3] . Variables were compared by sample t-test. Bivariate linear correlation was estimated using Pearson’s correlation coefficient. Linear regression analysis was applied to investigate the association between IMs and anthropometric and biochemical variables. Results: The mean age of participants was 46.1±16.1 years. abdominal obesity was present in 199(56.5%) individuals. levels of hs-CRP and IL-6 increased in the abdominally obese group (1507±3.3 vs. 577.8±4.3 ng/ml Phttp://ijbms.mums.ac.ir/pdf_3189_7576c6383629cf3af4d6666eb3f2f81e.htmlHcy hs-CRP IL-6 Inflammatory markers Obesity TLGS |
| spellingShingle | Bita Faam Maryam Zarkesh Maryam Sadat Daneshpour Fereidoun Azizi Mehdi Hedayati The association between inflammatory markers and obesity-related factors in Tehranian adults: Tehran lipid and glucose study Iranian Journal of Basic Medical Sciences Hcy hs-CRP IL-6 Inflammatory markers Obesity TLGS |
| title | The association between inflammatory markers and obesity-related factors in Tehranian adults: Tehran lipid and glucose study |
| title_full | The association between inflammatory markers and obesity-related factors in Tehranian adults: Tehran lipid and glucose study |
| title_fullStr | The association between inflammatory markers and obesity-related factors in Tehranian adults: Tehran lipid and glucose study |
| title_full_unstemmed | The association between inflammatory markers and obesity-related factors in Tehranian adults: Tehran lipid and glucose study |
| title_short | The association between inflammatory markers and obesity-related factors in Tehranian adults: Tehran lipid and glucose study |
| title_sort | association between inflammatory markers and obesity related factors in tehranian adults tehran lipid and glucose study |
| topic | Hcy hs-CRP IL-6 Inflammatory markers Obesity TLGS |
| url | http://ijbms.mums.ac.ir/pdf_3189_7576c6383629cf3af4d6666eb3f2f81e.html |
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