The European AntibotABE Framework Program and Its Update: Development of Innovative Botulinum Antibodies

The European AntibotABE Framework Program and Its Update: Development of Innovative Botulinum Antibodies

The goal of the AntiBotABE Program was the development of recombinant antibodies that neutralize botulinum neurotoxins (BoNT) A, B and E. These serotypes are lethal and responsible for most human botulinum cases. To improve therapeutic efficacy, the heavy and light chains (HC and LC) of the three Bo...

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Bibliographic Details
Main Authors: Christine Rasetti-Escargueil, Arnaud Avril, Sebastian Miethe, Christelle Mazuet, Yagmur Derman, Katja Selby, Philippe Thullier, Thibaut Pelat, Remi Urbain, Alexandre Fontayne, Hannu Korkeala, Dorothea Sesardic, Michael Hust, Michel R. Popoff
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Toxins
Subjects:
AntiBotABE
botulinum
toxin
phage-display
IgG
neutralization
botulism
biodefense
recombinant
oligoclonal antibodies
Online Access:https://www.mdpi.com/2072-6651/9/10/309

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