Effect of Ribavirin Alone or Combined with Silymarin on Carbon Tetrachloride Induced Hepatic Damage in Rats

Effect of Ribavirin Alone or Combined with Silymarin on Carbon Tetrachloride Induced Hepatic Damage in Rats

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The effect of the antiviral agent ribavirin given alone or in combination with silymarin on the development of liver injury induced in rats with carbon tetrachloride (CCl4; 2.8 ml/kg followed by 1.4 ml/kg after one week) was studied. Ribavirin at three dose levels (30, 60 or 90 mg/kg), silymarin (25...

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Bibliographic Details
Main Authors: Omar M.E. Abdel Salam, Amany A. Sleem, Enayat A. Omara, Nabila S. Hassan
Format: Article
Language:English
Published: AboutScience Srl 2007-01-01
Series:Drug Target Insights
Subjects:
Ribavirin
silymarin
carbon tetrachloride
liver injury
rat
Online Access:http://la-press.com/article.php?article_id=80

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