The Blockade of Store-Operated Calcium Channels Improves Decompression Sickness in Rats

The Blockade of Store-Operated Calcium Channels Improves Decompression Sickness in Rats

BackgroundPrevious investigations reveal that BTP2, a store-operated calcium channel blocker, has protective and anti-inflammatory properties in multiple inflammatory diseases. This study investigates whether BTP2 can protect against decompression sickness (DCS) in a rat model.MethodsBTP2 (2 mg/kg)...

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Bibliographic Details
Main Authors: Shih-En Tang, Wen-I Liao, Shu-Yu Wu, Hsin-Ping Pao, Kun-Lun Huang, Shi-Jye Chu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Physiology
Subjects:
store-operated calcium channels
decompression sickness
lung injury
air embolism
BTP2
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01616/full

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