Chemical and biological investigations of Dillenia indica Linn.
A total of four compounds namely, lupeol (1), betulinaldehyde (2), betulinic acid (3) and stigmasterol (4) were isolated from the stem extract of Dillenia indica Linn. The structures of the isolated compounds (1-4) were established by extensive spectroscopic studies. The crude methanolic extracts an...
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| Format: | Article |
| Language: | English |
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Bangladesh Pharmacological Society
2009-07-01
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| Series: | Bangladesh Journal of Pharmacology |
| Subjects: | |
| Online Access: | https://www.banglajol.info/index.php/BJP/article/view/2758 |
| _version_ | 1818569712221552640 |
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| author | Most. Nazma Parvin Mohammad S. Rahman Mohammad S. Islam Mohammad A. Rashid |
| author_facet | Most. Nazma Parvin Mohammad S. Rahman Mohammad S. Islam Mohammad A. Rashid |
| author_sort | Most. Nazma Parvin |
| collection | DOAJ |
| description | A total of four compounds namely, lupeol (1), betulinaldehyde (2), betulinic acid (3) and stigmasterol (4) were isolated from the stem extract of Dillenia indica Linn. The structures of the isolated compounds (1-4) were established by extensive spectroscopic studies. The crude methanolic extracts and its n-hexane, carbon tetrachloride, dichloromethane and chloroform soluble partitionates demonstrated weak antimicrobial activity against a wide range of Gram-positive and Gram-negative bacteria and fungi. The extractives revealed significant cytotoxic activity when tested by brine shrimp lethality bioassay. In addition, the extractives exhibited significant free radical scavenging activity when compared with the standard drug ascorbic acid. |
| first_indexed | 2024-12-14T06:51:22Z |
| format | Article |
| id | doaj.art-424c854c9962426bbbbfe6e4c6331838 |
| institution | Directory Open Access Journal |
| issn | 1991-0088 |
| language | English |
| last_indexed | 2024-12-14T06:51:22Z |
| publishDate | 2009-07-01 |
| publisher | Bangladesh Pharmacological Society |
| record_format | Article |
| series | Bangladesh Journal of Pharmacology |
| spelling | doaj.art-424c854c9962426bbbbfe6e4c63318382022-12-21T23:12:53ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-00882009-07-014210.3329/bjp.v4i2.2758Chemical and biological investigations of Dillenia indica Linn.Most. Nazma Parvin0Mohammad S. Rahman1Mohammad S. Islam2Mohammad A. Rashid3Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka 1000Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka 1000Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1000A total of four compounds namely, lupeol (1), betulinaldehyde (2), betulinic acid (3) and stigmasterol (4) were isolated from the stem extract of Dillenia indica Linn. The structures of the isolated compounds (1-4) were established by extensive spectroscopic studies. The crude methanolic extracts and its n-hexane, carbon tetrachloride, dichloromethane and chloroform soluble partitionates demonstrated weak antimicrobial activity against a wide range of Gram-positive and Gram-negative bacteria and fungi. The extractives revealed significant cytotoxic activity when tested by brine shrimp lethality bioassay. In addition, the extractives exhibited significant free radical scavenging activity when compared with the standard drug ascorbic acid.https://www.banglajol.info/index.php/BJP/article/view/2758AntimicrobialAntioxidantCytotoxicityDillenia indica |
| spellingShingle | Most. Nazma Parvin Mohammad S. Rahman Mohammad S. Islam Mohammad A. Rashid Chemical and biological investigations of Dillenia indica Linn. Bangladesh Journal of Pharmacology Antimicrobial Antioxidant Cytotoxicity Dillenia indica |
| title | Chemical and biological investigations of Dillenia indica Linn. |
| title_full | Chemical and biological investigations of Dillenia indica Linn. |
| title_fullStr | Chemical and biological investigations of Dillenia indica Linn. |
| title_full_unstemmed | Chemical and biological investigations of Dillenia indica Linn. |
| title_short | Chemical and biological investigations of Dillenia indica Linn. |
| title_sort | chemical and biological investigations of dillenia indica linn |
| topic | Antimicrobial Antioxidant Cytotoxicity Dillenia indica |
| url | https://www.banglajol.info/index.php/BJP/article/view/2758 |
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