Cytidine-phosphate-guanosine oligodeoxynucleotides in combination with CD40 ligand decrease periodontal inflammation and alveolar bone loss in a TLR9-independent manner

Cytidine-phosphate-guanosine oligodeoxynucleotides in combination with CD40 ligand decrease periodontal inflammation and alveolar bone loss in a TLR9-independent manner

Abstract Local administration of toll-like receptor 9 (TLR9), agonist cytidine-phosphate-guanosine oligodeoxynucleotide (CpG ODNs), and CD40 ligand (CD40L) can decrease ligature-induced periodontal inflammation and bone loss in wild type (WT) mouse. Objective: This study aimed to explore whether su...

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Bibliographic Details
Main Authors:	Qian Zhao, Yang Hu, Shu Deng, Pei Yu, Bowen Chen, Zuomin Wang, Xiaozhe Han
Format:	Article
Language:	English
Published:	University of São Paulo 2018-05-01
Series:	Journal of Applied Oral Science
Subjects:	CpG Inflammation Periodontitis Toll-like receptor 9
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572018000100458&lng=en&tlng=en

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