Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle

Klotho expression is a prerequisite for proper muscle stem cell function and regeneration of skeletal muscle

Abstract Background Klotho is a well-known anti-aging hormone, which serves as a suppressor of aging through a variety of mechanisms. Aging of skeletal muscle is concomitant with a decrease in muscle stem cell function resulting in impaired regeneration. Methods Here we investigate the functional ro...

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Bibliographic Details
Main Authors: Hellen E. Ahrens, Judith Huettemeister, Manuel Schmidt, Christoph Kaether, Julia von Maltzahn
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Skeletal Muscle
Subjects:
Skeletal muscle
Regeneration
Klotho
Myogenesis
Muscle stem cell
Aging
Online Access:http://link.springer.com/article/10.1186/s13395-018-0166-x

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