MgrB variants in colistin-susceptible and colistin-resistant Klebsiella pneumoniae ST258

Resistance determinants of a colistin susceptible and five colistin resistant Klebsiella pneumoniae ST258 from a Hungarian outbreak were investigated. A novel MgrB variant in colistin susceptible strain was found. Elevated phoP and arn gene expressions and wild-type PmrB in all colistin resistant K....

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Main Authors: Béla Kocsis, Béla Kádár
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Journal of Microbiology, Immunology and Infection
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1684118216300718
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author Béla Kocsis
Béla Kádár
author_facet Béla Kocsis
Béla Kádár
author_sort Béla Kocsis
collection DOAJ
description Resistance determinants of a colistin susceptible and five colistin resistant Klebsiella pneumoniae ST258 from a Hungarian outbreak were investigated. A novel MgrB variant in colistin susceptible strain was found. Elevated phoP and arn gene expressions and wild-type PmrB in all colistin resistant K. pneumoniae were detected. All strains lacked mcr-1.
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spelling doaj.art-425099c5d46e4539aba6f08be7f56fbf2022-12-21T18:54:11ZengElsevierJournal of Microbiology, Immunology and Infection1684-11822017-10-0150573573610.1016/j.jmii.2016.06.008MgrB variants in colistin-susceptible and colistin-resistant Klebsiella pneumoniae ST258Béla KocsisBéla KádárResistance determinants of a colistin susceptible and five colistin resistant Klebsiella pneumoniae ST258 from a Hungarian outbreak were investigated. A novel MgrB variant in colistin susceptible strain was found. Elevated phoP and arn gene expressions and wild-type PmrB in all colistin resistant K. pneumoniae were detected. All strains lacked mcr-1.http://www.sciencedirect.com/science/article/pii/S1684118216300718Colistin resistanceKlebsiella pneumoniaeMgrBPmrB
spellingShingle Béla Kocsis
Béla Kádár
MgrB variants in colistin-susceptible and colistin-resistant Klebsiella pneumoniae ST258
Journal of Microbiology, Immunology and Infection
Colistin resistance
Klebsiella pneumoniae
MgrB
PmrB
title MgrB variants in colistin-susceptible and colistin-resistant Klebsiella pneumoniae ST258
title_full MgrB variants in colistin-susceptible and colistin-resistant Klebsiella pneumoniae ST258
title_fullStr MgrB variants in colistin-susceptible and colistin-resistant Klebsiella pneumoniae ST258
title_full_unstemmed MgrB variants in colistin-susceptible and colistin-resistant Klebsiella pneumoniae ST258
title_short MgrB variants in colistin-susceptible and colistin-resistant Klebsiella pneumoniae ST258
title_sort mgrb variants in colistin susceptible and colistin resistant klebsiella pneumoniae st258
topic Colistin resistance
Klebsiella pneumoniae
MgrB
PmrB
url http://www.sciencedirect.com/science/article/pii/S1684118216300718
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