Comparison of the three dressing methods on the speed of repair and remaining scar on partial-thickness skin graft donor sites in burn patients
Background: Rapid repair of skin donor sites in partial-thickness skin grafts in burn is critical to the patient. Severe pain during dressing change and scarring also reduce the quality of life and treatment. Recently, nano-silver particles are available which have a high surface to volume ratio and...
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| Format: | Article |
| Language: | fas |
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Tehran University of Medical Sciences
2019-09-01
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| Series: | Tehran University Medical Journal |
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| Online Access: | http://tumj.tums.ac.ir/article-1-9922-en.html |
| _version_ | 1818282971002568704 |
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| author | Mahnoush Momeni Mohammd Javad Fatemi Bita Kamranfar Mohsen Saberi Tooran Bagheri Mitra Niazi |
| author_facet | Mahnoush Momeni Mohammd Javad Fatemi Bita Kamranfar Mohsen Saberi Tooran Bagheri Mitra Niazi |
| author_sort | Mahnoush Momeni |
| collection | DOAJ |
| description | Background: Rapid repair of skin donor sites in partial-thickness skin grafts in burn is critical to the patient. Severe pain during dressing change and scarring also reduce the quality of life and treatment. Recently, nano-silver particles are available which have a high surface to volume ratio and remain effective even at a very low concentration and minimize the chance for tissue toxicity due to silver. Our aim in this study was to evaluate the effect of nano-silver dressings on increasing the rate of repair and reduction of complications in non-infectious wounds of skin graft donor sites.
Methods: This was comparison study that involved patients admitted to a single-center burn unit who required a skin graft donor site. 10 burn patients with thermal injury and 10-30% of total body surface area (TBSA) who referred to Shahid Motahari Hospital, Tehran, in 2016 were studied. Each patient was compared to herself. After anesthesia, the site of the skin graft was randomly divided into three sections in each patient and was covered with Agicoat®, Mepitel and vaseline gauze. On the 4th and 8th of the day, the pain was recorded during the dressing change on the basis of the visual analogue scale (VAS). After 6 months, the patients were evaluated for the remainder of the scars based on VSS (Vancouver scar scale).
Results: The mean time to repair in both groups were similar and significantly shorter than that of vaseline (P=0.005). The pain comparison between groups showed that on the fourth day, the mean pain in the Agicoat group and Mepitel was significantly less than the Vaseline group (P=0.004). Also, the mean pain of the epileptic group was significantly lower than that of the Vaseline group (0.002). However, there was no significant difference between the duration of regeneration and pain between the two groups of Agicoat and Mepitel, but there was no significant difference between the mean pain on the 8th day and the mean VAS 6 months after the graft.
Conclusion: Agicoat dressing has been effective in reducing pain and increasing the repair speed, but this effect was similar to that of the silver-free Mepitel dressing. Expensive silver nano-crystal dressings limit their use. The silver nanocrystal did not have much effect on improving the remaining scar. However, more studies are needed in this regard. |
| first_indexed | 2024-12-13T00:29:29Z |
| format | Article |
| id | doaj.art-425134e4b77a467fbbcf6afb2c3a99e8 |
| institution | Directory Open Access Journal |
| issn | 1683-1764 1735-7322 |
| language | fas |
| last_indexed | 2024-12-13T00:29:29Z |
| publishDate | 2019-09-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Tehran University Medical Journal |
| spelling | doaj.art-425134e4b77a467fbbcf6afb2c3a99e82022-12-22T00:05:21ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222019-09-01776352358Comparison of the three dressing methods on the speed of repair and remaining scar on partial-thickness skin graft donor sites in burn patientsMahnoush Momeni0Mohammd Javad Fatemi1Bita Kamranfar2Mohsen Saberi3Tooran Bagheri4Mitra Niazi5 Department of General Surgery, Burn Research Center, Iran University of Medical Sciences, Tehran, Iran. Department of Plastic and Reconstructive Surgery, Burn Research Center, Iran University of Medical Sciences, Tehran, Iran. Department of Nursing, Shahid Motahari Hospital, Iran University of Medical Sciences, Tehran, Iran. Department of Community Medicine, Medicine, Quran and Hadith Research Center, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran. Department of Nursing, Burn Research Center, Iran University of Medical Sciences, Tehran, Iran. Department of Occupational Therapy, Burn Research Center, Iran University of Medical Sciences, Tehran, Iran. Background: Rapid repair of skin donor sites in partial-thickness skin grafts in burn is critical to the patient. Severe pain during dressing change and scarring also reduce the quality of life and treatment. Recently, nano-silver particles are available which have a high surface to volume ratio and remain effective even at a very low concentration and minimize the chance for tissue toxicity due to silver. Our aim in this study was to evaluate the effect of nano-silver dressings on increasing the rate of repair and reduction of complications in non-infectious wounds of skin graft donor sites. Methods: This was comparison study that involved patients admitted to a single-center burn unit who required a skin graft donor site. 10 burn patients with thermal injury and 10-30% of total body surface area (TBSA) who referred to Shahid Motahari Hospital, Tehran, in 2016 were studied. Each patient was compared to herself. After anesthesia, the site of the skin graft was randomly divided into three sections in each patient and was covered with Agicoat®, Mepitel and vaseline gauze. On the 4th and 8th of the day, the pain was recorded during the dressing change on the basis of the visual analogue scale (VAS). After 6 months, the patients were evaluated for the remainder of the scars based on VSS (Vancouver scar scale). Results: The mean time to repair in both groups were similar and significantly shorter than that of vaseline (P=0.005). The pain comparison between groups showed that on the fourth day, the mean pain in the Agicoat group and Mepitel was significantly less than the Vaseline group (P=0.004). Also, the mean pain of the epileptic group was significantly lower than that of the Vaseline group (0.002). However, there was no significant difference between the duration of regeneration and pain between the two groups of Agicoat and Mepitel, but there was no significant difference between the mean pain on the 8th day and the mean VAS 6 months after the graft. Conclusion: Agicoat dressing has been effective in reducing pain and increasing the repair speed, but this effect was similar to that of the silver-free Mepitel dressing. Expensive silver nano-crystal dressings limit their use. The silver nanocrystal did not have much effect on improving the remaining scar. However, more studies are needed in this regard.http://tumj.tums.ac.ir/article-1-9922-en.htmlburnsskin transplantationtransplant donor site |
| spellingShingle | Mahnoush Momeni Mohammd Javad Fatemi Bita Kamranfar Mohsen Saberi Tooran Bagheri Mitra Niazi Comparison of the three dressing methods on the speed of repair and remaining scar on partial-thickness skin graft donor sites in burn patients Tehran University Medical Journal burns skin transplantation transplant donor site |
| title | Comparison of the three dressing methods on the speed of repair and remaining scar on partial-thickness skin graft donor sites in burn patients |
| title_full | Comparison of the three dressing methods on the speed of repair and remaining scar on partial-thickness skin graft donor sites in burn patients |
| title_fullStr | Comparison of the three dressing methods on the speed of repair and remaining scar on partial-thickness skin graft donor sites in burn patients |
| title_full_unstemmed | Comparison of the three dressing methods on the speed of repair and remaining scar on partial-thickness skin graft donor sites in burn patients |
| title_short | Comparison of the three dressing methods on the speed of repair and remaining scar on partial-thickness skin graft donor sites in burn patients |
| title_sort | comparison of the three dressing methods on the speed of repair and remaining scar on partial thickness skin graft donor sites in burn patients |
| topic | burns skin transplantation transplant donor site |
| url | http://tumj.tums.ac.ir/article-1-9922-en.html |
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