Contrast-enhanced ultrasound in the diagnosis of infiltrative hepatocellular carcinoma: A report of three cases
Infiltrative hepatocellular carcinoma (HCC) is a challenging imaging diagnosis due to its ill-defined appearance and variable enhancement, which may be difficult to distinguish from background changes from cirrhosis. The literature on the role of contrast-enhanced ultrasound (CEUS) in the diagnosis...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-03-01
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| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043320306191 |
| _version_ | 1818561281783758848 |
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| author | Yasovineeth Bhogadi, BSc Ethan Brown, MB, BCh, BAO Stefanie Y. Lee, MD, FRCPC |
| author_facet | Yasovineeth Bhogadi, BSc Ethan Brown, MB, BCh, BAO Stefanie Y. Lee, MD, FRCPC |
| author_sort | Yasovineeth Bhogadi, BSc |
| collection | DOAJ |
| description | Infiltrative hepatocellular carcinoma (HCC) is a challenging imaging diagnosis due to its ill-defined appearance and variable enhancement, which may be difficult to distinguish from background changes from cirrhosis. The literature on the role of contrast-enhanced ultrasound (CEUS) in the diagnosis of infiltrative HCC is currently limited. CEUS has greater sensitivity for contrast enhancement due to its temporal resolution, and can be used when there is contraindication to CT or MRI contrast. We present 3 cases where CEUS aided in the diagnosis of infiltrative HCC in patients with equivocal CT and MRI findings and/or renal failure, with significant implications for management. As current guidelines focus on the role of CEUS in characterizing defined focal liver lesions or discrete observations on precontrast US, further studies are warranted to validate the utility of CEUS in the noninvasive diagnosis of infiltrative HCC and delineate its role in algorithms for imaging workup. |
| first_indexed | 2024-12-14T00:48:49Z |
| format | Article |
| id | doaj.art-42533ac71a7f412cb395433c87518004 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-12-14T00:48:49Z |
| publishDate | 2021-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-42533ac71a7f412cb395433c875180042022-12-21T23:23:58ZengElsevierRadiology Case Reports1930-04332021-03-01163448456Contrast-enhanced ultrasound in the diagnosis of infiltrative hepatocellular carcinoma: A report of three casesYasovineeth Bhogadi, BSc0Ethan Brown, MB, BCh, BAO1Stefanie Y. Lee, MD, FRCPC2Michael G DeGroote School of Medicine, McMaster University, Hamilton, Ontario, CanadaDepartment of Medical Imaging, University of Toronto, Toronto, Ontario, CanadaDepartment of Radiology, McMaster University; Hamilton Health Sciences, Juravinski Hospital and Cancer Centre, Hamilton, Ontario, Canada; Corresponding author:Infiltrative hepatocellular carcinoma (HCC) is a challenging imaging diagnosis due to its ill-defined appearance and variable enhancement, which may be difficult to distinguish from background changes from cirrhosis. The literature on the role of contrast-enhanced ultrasound (CEUS) in the diagnosis of infiltrative HCC is currently limited. CEUS has greater sensitivity for contrast enhancement due to its temporal resolution, and can be used when there is contraindication to CT or MRI contrast. We present 3 cases where CEUS aided in the diagnosis of infiltrative HCC in patients with equivocal CT and MRI findings and/or renal failure, with significant implications for management. As current guidelines focus on the role of CEUS in characterizing defined focal liver lesions or discrete observations on precontrast US, further studies are warranted to validate the utility of CEUS in the noninvasive diagnosis of infiltrative HCC and delineate its role in algorithms for imaging workup.http://www.sciencedirect.com/science/article/pii/S1930043320306191Contrast-enhanced ultrasoundInfiltrative hepatocellular carcinoma |
| spellingShingle | Yasovineeth Bhogadi, BSc Ethan Brown, MB, BCh, BAO Stefanie Y. Lee, MD, FRCPC Contrast-enhanced ultrasound in the diagnosis of infiltrative hepatocellular carcinoma: A report of three cases Radiology Case Reports Contrast-enhanced ultrasound Infiltrative hepatocellular carcinoma |
| title | Contrast-enhanced ultrasound in the diagnosis of infiltrative hepatocellular carcinoma: A report of three cases |
| title_full | Contrast-enhanced ultrasound in the diagnosis of infiltrative hepatocellular carcinoma: A report of three cases |
| title_fullStr | Contrast-enhanced ultrasound in the diagnosis of infiltrative hepatocellular carcinoma: A report of three cases |
| title_full_unstemmed | Contrast-enhanced ultrasound in the diagnosis of infiltrative hepatocellular carcinoma: A report of three cases |
| title_short | Contrast-enhanced ultrasound in the diagnosis of infiltrative hepatocellular carcinoma: A report of three cases |
| title_sort | contrast enhanced ultrasound in the diagnosis of infiltrative hepatocellular carcinoma a report of three cases |
| topic | Contrast-enhanced ultrasound Infiltrative hepatocellular carcinoma |
| url | http://www.sciencedirect.com/science/article/pii/S1930043320306191 |
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