Ubiquitination in T-Cell Activation and Checkpoint Inhibition: New Avenues for Targeted Cancer Immunotherapy
The advent of T-cell-based immunotherapy has remarkably transformed cancer patient treatment. Despite their success, the currently approved immunotherapeutic protocols still encounter limitations, cause toxicity, and give disparate patient outcomes. Thus, a deeper understanding of the molecular mech...
Main Authors: | Shubhangi Gavali, Jianing Liu, Xinyi Li, Magdalena Paolino |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-10-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/19/10800 |
Similar Items
-
E3 ubiquitin ligases and deubiquitinases in bladder cancer tumorigenesis and implications for immunotherapies
by: Maoyu Wang, et al.
Published: (2023-07-01) -
Autophagy Regulation by Crosstalk between miRNAs and Ubiquitination System
by: Junyan Qu, et al.
Published: (2021-11-01) -
Editorial: Ubiquitin and ubiquitin-like modifications in viral infection and innate immunity
by: Konstantin M. J. Sparrer, et al.
Published: (2023-02-01) -
The Multifaceted Role of the Ubiquitin Proteasome System in Pathogenesis and Diseases
by: Zane Stekel, et al.
Published: (2022-07-01) -
Mcl-1 Ubiquitination: Unique Regulation of an Essential Survival Protein
by: Barbara Mojsa, et al.
Published: (2014-05-01)