Benign Recurrent Intrahepatic Cholestasis in a Young Adult

Benign Recurrent Intrahepatic Cholestasis (BRIC) is a rare genetic disorder characterized by recurrent episodes of cholestatic jaundice. The initial episode of jaundice generally occurs before second decade of life and can persist for several weeks to months before resolving spontaneously. It is a...

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Main Authors: Prabhat Kumar, Riyaz Charaniya, Arvind Ahuja, Sakshi Mittal, Ratnakar Sahoo
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2016-06-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/7924/18917_CE(Ra1)_F(GH)_PF1(VIAK)_PFA(AK)_PF2(PAG).pdf
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author Prabhat Kumar
Riyaz Charaniya
Arvind Ahuja
Sakshi Mittal
Ratnakar Sahoo
author_facet Prabhat Kumar
Riyaz Charaniya
Arvind Ahuja
Sakshi Mittal
Ratnakar Sahoo
author_sort Prabhat Kumar
collection DOAJ
description Benign Recurrent Intrahepatic Cholestasis (BRIC) is a rare genetic disorder characterized by recurrent episodes of cholestatic jaundice. The initial episode of jaundice generally occurs before second decade of life and can persist for several weeks to months before resolving spontaneously. It is a benign disease and even after repeated episodes of jaundice, fibrosis of liver cell does not occur. We had a young adult patient who was having recurrent episodes of cholestatic jaundice with intervening symptom free period for last 20 years. He had first episode of jaundice at the age of eight and since then had several similar episodes. Diagnosis was made by classical clinical presentation and histopathological findings. We intend to report this case due to rarity of this disease in India.
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spelling doaj.art-4261b61afdc041d78f22bd826e230e432022-12-22T01:29:26ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-06-01106OD01OD0210.7860/JCDR/2016/18917.7924Benign Recurrent Intrahepatic Cholestasis in a Young AdultPrabhat Kumar0Riyaz Charaniya1Arvind Ahuja2Sakshi Mittal3Ratnakar Sahoo4Senior Resident, Department of Medicine, PGIMER & Dr RML Hospital, New Delhi, India.Postgraduate Resident, Department of Medicine, PGIMER & Dr RML Hospital, New Delhi, India.Associate Professor, Department of Pathology, PGIMER & Dr RML Hospital, New Delhi, India.Senior Resident, Department of Medicine, PGIMER & Dr RML Hospital, New Delhi, India.Professor, Department of Medicine, PGIMER & Dr RML Hospital, New Delhi, India.Benign Recurrent Intrahepatic Cholestasis (BRIC) is a rare genetic disorder characterized by recurrent episodes of cholestatic jaundice. The initial episode of jaundice generally occurs before second decade of life and can persist for several weeks to months before resolving spontaneously. It is a benign disease and even after repeated episodes of jaundice, fibrosis of liver cell does not occur. We had a young adult patient who was having recurrent episodes of cholestatic jaundice with intervening symptom free period for last 20 years. He had first episode of jaundice at the age of eight and since then had several similar episodes. Diagnosis was made by classical clinical presentation and histopathological findings. We intend to report this case due to rarity of this disease in India.https://jcdr.net/articles/PDF/7924/18917_CE(Ra1)_F(GH)_PF1(VIAK)_PFA(AK)_PF2(PAG).pdfcholestatic jaundicepruritusrifampicin
spellingShingle Prabhat Kumar
Riyaz Charaniya
Arvind Ahuja
Sakshi Mittal
Ratnakar Sahoo
Benign Recurrent Intrahepatic Cholestasis in a Young Adult
Journal of Clinical and Diagnostic Research
cholestatic jaundice
pruritus
rifampicin
title Benign Recurrent Intrahepatic Cholestasis in a Young Adult
title_full Benign Recurrent Intrahepatic Cholestasis in a Young Adult
title_fullStr Benign Recurrent Intrahepatic Cholestasis in a Young Adult
title_full_unstemmed Benign Recurrent Intrahepatic Cholestasis in a Young Adult
title_short Benign Recurrent Intrahepatic Cholestasis in a Young Adult
title_sort benign recurrent intrahepatic cholestasis in a young adult
topic cholestatic jaundice
pruritus
rifampicin
url https://jcdr.net/articles/PDF/7924/18917_CE(Ra1)_F(GH)_PF1(VIAK)_PFA(AK)_PF2(PAG).pdf
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AT arvindahuja benignrecurrentintrahepaticcholestasisinayoungadult
AT sakshimittal benignrecurrentintrahepaticcholestasisinayoungadult
AT ratnakarsahoo benignrecurrentintrahepaticcholestasisinayoungadult