Venlafaxine and L-Thyroxine Treatment Combination: Impact on Metabolic and Synaptic Plasticity Changes in an Animal Model of Coexisting Depression and Hypothyroidism

Venlafaxine and L-Thyroxine Treatment Combination: Impact on Metabolic and Synaptic Plasticity Changes in an Animal Model of Coexisting Depression and Hypothyroidism

The clinical effectiveness of supportive therapy with thyroid hormones in drug-resistant depression is well-known; however, the mechanisms of action of these hormones in the adult brain have not been fully elucidated to date. We determined the effects of venlafaxine and/or L-thyroxine on metabolic p...

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Bibliographic Details
Main Authors: Katarzyna Głombik, Jan Detka, Bogusława Budziszewska
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cells
Subjects:
depression
hypothyroidism
animal disease models
levothyroxine
venlafaxine
glycolysis
Online Access:https://www.mdpi.com/2073-4409/10/6/1394

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