Expression of Cholera Toxin (CT) and the Toxin Co-Regulated Pilus (TCP) by Variants of ToxT in <i>Vibrio cholerae</i> Strains

Expression of Cholera Toxin (CT) and the Toxin Co-Regulated Pilus (TCP) by Variants of ToxT in <i>Vibrio cholerae</i> Strains

The expression of the two major virulence genes of <i>Vibrio cholerae</i>—<i>tcpA</i> (the major subunit of the toxin co-regulated pilus) and <i>ctxAB</i> (cholera toxin)—is regulated by the ToxR regulon, which is triggered by environmental stimuli during infectio...

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Bibliographic Details
Main Authors: Donghyun Lee, Hunseok Choi, Seonghyeon Son, Jonghyun Bae, Jayun Joo, Dong Wook Kim, Eun Jin Kim
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Toxins
Subjects:
cholera
<i>Vibrio cholerae</i>
cholera toxin (CT)
toxin co-regulated pilus (TCP)
ToxT
Online Access:https://www.mdpi.com/2072-6651/15/8/507

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