The effectiveness of mindfulness yoga on patients with major depressive disorder: a systematic review and meta-analysis of randomized controlled trials

Abstract Background Mindfulness yoga is a type of exercise that emphasizes the integration of mindfulness or meditation into yoga. The aim of this study was to determine the effectiveness of mindfulness yoga intervention on major depressive disorder (MDD) patients. Methods A systematic review and me...

Full description

Bibliographic Details
Main Authors: Chuyuan Miao, Yun Gao, Xiaohua Li, Ying Zhou, Joanne Wai-yee Chung, Graeme D. Smith
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Online Access:https://doi.org/10.1186/s12906-023-04141-2
_version_ 1797453870221230080
author Chuyuan Miao
Yun Gao
Xiaohua Li
Ying Zhou
Joanne Wai-yee Chung
Graeme D. Smith
author_facet Chuyuan Miao
Yun Gao
Xiaohua Li
Ying Zhou
Joanne Wai-yee Chung
Graeme D. Smith
author_sort Chuyuan Miao
collection DOAJ
description Abstract Background Mindfulness yoga is a type of exercise that emphasizes the integration of mindfulness or meditation into yoga. The aim of this study was to determine the effectiveness of mindfulness yoga intervention on major depressive disorder (MDD) patients. Methods A systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted by searching nine databases, including PubMed, EMBASE, Web of Science, The Cochrane Library, MEDLINE, China National Knowledge Infrastructure (CNKI), Wanfang Data knowledge service platform, Chinese Biomedical Literature Database (CBM), and China Science and Technology Journal Database (VIP) from inception to April 2023. Primary outcomes included the severity of depression. Secondary outcomes included anxiety and rumination. Results Nine RCTs met our inclusion criteria (n = 581). The meta-analysis showed that mindfulness yoga significantly has a significant effect on depression (SMD = -0.53; 95%CI = -0.96 to -0.11; P < 0.05) among MDD patients. The only two RCTs involved also showed that mindfulness yoga could alleviate the anxiety level of MDD patients after intervention (SMD = -1.08; 95%CI = -1.64 to -0.52; P < 0.05). Meta-analysis did not reveal positive effects of the mindfulness yoga groups on rumination after intervention based on three RCTs (SMD = -0.33; 95%CI = -0.89 to 0.23; P > 0.05), but found a significant difference in the follow-up period based on two RCTs (MD = -7.42; 95%CI = -11.27 to -3.56; P < 0.05), compared with the control groups. Conclusion Although we were unable to provide conclusive evidence to support the effectiveness of mindfulness yoga in improving symptoms in MDD patients, we found the literature included in this study indicated that mindfulness yoga might have a potential benefit for MDD patients and should be a feasible, acceptable, and promising intervention.
first_indexed 2024-03-09T15:29:07Z
format Article
id doaj.art-426baf2fc2a6454e969810e457366733
institution Directory Open Access Journal
issn 2662-7671
language English
last_indexed 2024-03-09T15:29:07Z
publishDate 2023-09-01
publisher BMC
record_format Article
series BMC Complementary Medicine and Therapies
spelling doaj.art-426baf2fc2a6454e969810e4573667332023-11-26T12:19:54ZengBMCBMC Complementary Medicine and Therapies2662-76712023-09-0123111310.1186/s12906-023-04141-2The effectiveness of mindfulness yoga on patients with major depressive disorder: a systematic review and meta-analysis of randomized controlled trialsChuyuan Miao0Yun Gao1Xiaohua Li2Ying Zhou3Joanne Wai-yee Chung4Graeme D. Smith5School of Nursing, Guangzhou Medical UniversitySchool of Nursing, Guangzhou Medical UniversitySchool of Nursing, Guangzhou Medical UniversitySchool of Nursing, Guangzhou Medical UniversitySchool of Nursing, Guangzhou Medical UniversitySchool of Health Sciences, Caritas Institute of Higher EducationAbstract Background Mindfulness yoga is a type of exercise that emphasizes the integration of mindfulness or meditation into yoga. The aim of this study was to determine the effectiveness of mindfulness yoga intervention on major depressive disorder (MDD) patients. Methods A systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted by searching nine databases, including PubMed, EMBASE, Web of Science, The Cochrane Library, MEDLINE, China National Knowledge Infrastructure (CNKI), Wanfang Data knowledge service platform, Chinese Biomedical Literature Database (CBM), and China Science and Technology Journal Database (VIP) from inception to April 2023. Primary outcomes included the severity of depression. Secondary outcomes included anxiety and rumination. Results Nine RCTs met our inclusion criteria (n = 581). The meta-analysis showed that mindfulness yoga significantly has a significant effect on depression (SMD = -0.53; 95%CI = -0.96 to -0.11; P < 0.05) among MDD patients. The only two RCTs involved also showed that mindfulness yoga could alleviate the anxiety level of MDD patients after intervention (SMD = -1.08; 95%CI = -1.64 to -0.52; P < 0.05). Meta-analysis did not reveal positive effects of the mindfulness yoga groups on rumination after intervention based on three RCTs (SMD = -0.33; 95%CI = -0.89 to 0.23; P > 0.05), but found a significant difference in the follow-up period based on two RCTs (MD = -7.42; 95%CI = -11.27 to -3.56; P < 0.05), compared with the control groups. Conclusion Although we were unable to provide conclusive evidence to support the effectiveness of mindfulness yoga in improving symptoms in MDD patients, we found the literature included in this study indicated that mindfulness yoga might have a potential benefit for MDD patients and should be a feasible, acceptable, and promising intervention.https://doi.org/10.1186/s12906-023-04141-2YogaMindfulnessDepressionMajor depressive disorderMeta-analysisSystematic review
spellingShingle Chuyuan Miao
Yun Gao
Xiaohua Li
Ying Zhou
Joanne Wai-yee Chung
Graeme D. Smith
The effectiveness of mindfulness yoga on patients with major depressive disorder: a systematic review and meta-analysis of randomized controlled trials
BMC Complementary Medicine and Therapies
Yoga
Mindfulness
Depression
Major depressive disorder
Meta-analysis
Systematic review
title The effectiveness of mindfulness yoga on patients with major depressive disorder: a systematic review and meta-analysis of randomized controlled trials
title_full The effectiveness of mindfulness yoga on patients with major depressive disorder: a systematic review and meta-analysis of randomized controlled trials
title_fullStr The effectiveness of mindfulness yoga on patients with major depressive disorder: a systematic review and meta-analysis of randomized controlled trials
title_full_unstemmed The effectiveness of mindfulness yoga on patients with major depressive disorder: a systematic review and meta-analysis of randomized controlled trials
title_short The effectiveness of mindfulness yoga on patients with major depressive disorder: a systematic review and meta-analysis of randomized controlled trials
title_sort effectiveness of mindfulness yoga on patients with major depressive disorder a systematic review and meta analysis of randomized controlled trials
topic Yoga
Mindfulness
Depression
Major depressive disorder
Meta-analysis
Systematic review
url https://doi.org/10.1186/s12906-023-04141-2
work_keys_str_mv AT chuyuanmiao theeffectivenessofmindfulnessyogaonpatientswithmajordepressivedisorderasystematicreviewandmetaanalysisofrandomizedcontrolledtrials
AT yungao theeffectivenessofmindfulnessyogaonpatientswithmajordepressivedisorderasystematicreviewandmetaanalysisofrandomizedcontrolledtrials
AT xiaohuali theeffectivenessofmindfulnessyogaonpatientswithmajordepressivedisorderasystematicreviewandmetaanalysisofrandomizedcontrolledtrials
AT yingzhou theeffectivenessofmindfulnessyogaonpatientswithmajordepressivedisorderasystematicreviewandmetaanalysisofrandomizedcontrolledtrials
AT joannewaiyeechung theeffectivenessofmindfulnessyogaonpatientswithmajordepressivedisorderasystematicreviewandmetaanalysisofrandomizedcontrolledtrials
AT graemedsmith theeffectivenessofmindfulnessyogaonpatientswithmajordepressivedisorderasystematicreviewandmetaanalysisofrandomizedcontrolledtrials
AT chuyuanmiao effectivenessofmindfulnessyogaonpatientswithmajordepressivedisorderasystematicreviewandmetaanalysisofrandomizedcontrolledtrials
AT yungao effectivenessofmindfulnessyogaonpatientswithmajordepressivedisorderasystematicreviewandmetaanalysisofrandomizedcontrolledtrials
AT xiaohuali effectivenessofmindfulnessyogaonpatientswithmajordepressivedisorderasystematicreviewandmetaanalysisofrandomizedcontrolledtrials
AT yingzhou effectivenessofmindfulnessyogaonpatientswithmajordepressivedisorderasystematicreviewandmetaanalysisofrandomizedcontrolledtrials
AT joannewaiyeechung effectivenessofmindfulnessyogaonpatientswithmajordepressivedisorderasystematicreviewandmetaanalysisofrandomizedcontrolledtrials
AT graemedsmith effectivenessofmindfulnessyogaonpatientswithmajordepressivedisorderasystematicreviewandmetaanalysisofrandomizedcontrolledtrials